K63 linked ubiquitin chain formation is a signal for HIF1A degradation by Chaperone-Mediated Autophagy

Chaperone-Mediated Autophagy is a selective form of autophagy. Recently, the degradation of a newly identified CMA substrate, the HIF1A transcription factor, was found to be regulated by the ubiquitin ligase STUB1. In this study we show, for the first time, that K63 ubiquitination is necessary for C...

Descripción completa

Detalles Bibliográficos
Autores principales: Vasco Ferreira, Joao, Rosa Soares, Ana, Silva Ramalho, Jose, Pereira, Paulo, Girao, Henrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426689/
https://www.ncbi.nlm.nih.gov/pubmed/25958982
http://dx.doi.org/10.1038/srep10210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426689/
https://www.ncbi.nlm.nih.gov/pubmed/25958982
http://dx.doi.org/10.1038/srep10210

Ejemplares similares