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With a Little Help from my Enteric Microbial Friends

Although the disciplines of bacteriology and virology frequently come together in the setting of a diagnostic medical microbiology laboratory, the two scientific fields are usually miles apart. The microbiologists basically form two non-overlapping groups of scientists, the bacteriologists and virol...

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Autor principal: Berkhout, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426759/
https://www.ncbi.nlm.nih.gov/pubmed/26029695
http://dx.doi.org/10.3389/fmed.2015.00030
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author Berkhout, Ben
author_facet Berkhout, Ben
author_sort Berkhout, Ben
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description Although the disciplines of bacteriology and virology frequently come together in the setting of a diagnostic medical microbiology laboratory, the two scientific fields are usually miles apart. The microbiologists basically form two non-overlapping groups of scientists, the bacteriologists and virologists, which go to separate meetings and do not easily intermingle. Some recent research findings about elegant virus–bacterium interactions may change this situation. Obviously, interactions between these two microbes can occur only when they colocalize, which most likely occurs in the gut/intestines where 10(14) commensal bacteria reside (the microbiota). We review findings on the following enteric microbial tandems: norovirus – Enterobacter cloacae, mouse mammary tumor virus (MMTV) – bacterial lipopolysaccharide (LPS), poliovirus and reovirus – intestinal bacteria. The close bacterium–virus interplay may also present options to develop unique therapeutic strategies for those infected, and to prevent further virus spread, and thus minimize the risk for the community.
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spelling pubmed-44267592015-05-29 With a Little Help from my Enteric Microbial Friends Berkhout, Ben Front Med (Lausanne) Medicine Although the disciplines of bacteriology and virology frequently come together in the setting of a diagnostic medical microbiology laboratory, the two scientific fields are usually miles apart. The microbiologists basically form two non-overlapping groups of scientists, the bacteriologists and virologists, which go to separate meetings and do not easily intermingle. Some recent research findings about elegant virus–bacterium interactions may change this situation. Obviously, interactions between these two microbes can occur only when they colocalize, which most likely occurs in the gut/intestines where 10(14) commensal bacteria reside (the microbiota). We review findings on the following enteric microbial tandems: norovirus – Enterobacter cloacae, mouse mammary tumor virus (MMTV) – bacterial lipopolysaccharide (LPS), poliovirus and reovirus – intestinal bacteria. The close bacterium–virus interplay may also present options to develop unique therapeutic strategies for those infected, and to prevent further virus spread, and thus minimize the risk for the community. Frontiers Media S.A. 2015-05-11 /pmc/articles/PMC4426759/ /pubmed/26029695 http://dx.doi.org/10.3389/fmed.2015.00030 Text en Copyright © 2015 Berkhout. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Medicine
Berkhout, Ben
With a Little Help from my Enteric Microbial Friends
title With a Little Help from my Enteric Microbial Friends
title_full With a Little Help from my Enteric Microbial Friends
title_fullStr With a Little Help from my Enteric Microbial Friends
title_full_unstemmed With a Little Help from my Enteric Microbial Friends
title_short With a Little Help from my Enteric Microbial Friends
title_sort with a little help from my enteric microbial friends
topic Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426759/
https://www.ncbi.nlm.nih.gov/pubmed/26029695
http://dx.doi.org/10.3389/fmed.2015.00030
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