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Sites of instability in the human TCF3 (E2A) gene adopt G-quadruplex DNA structures in vitro

The formation of highly stable four-stranded DNA, called G-quadruplex (G4), promotes site-specific genome instability. G4 DNA structures fold from repetitive guanine sequences, and increasing experimental evidence connects G4 sequence motifs with specific gene rearrangements. The human transcription...

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Detalles Bibliográficos
Autores principales:	Williams, Jonathan D., Fleetwood, Sara, Berroyer, Alexandra, Kim, Nayun, Larson, Erik D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426816/ https://www.ncbi.nlm.nih.gov/pubmed/26029241 http://dx.doi.org/10.3389/fgene.2015.00177

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