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scrm: efficiently simulating long sequences using the approximated coalescent with recombination
Motivation: Coalescent-based simulation software for genomic sequences allows the efficient in silico generation of short- and medium-sized genetic sequences. However, the simulation of genome-size datasets as produced by next-generation sequencing is currently only possible using fairly crude appro...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426833/ https://www.ncbi.nlm.nih.gov/pubmed/25596205 http://dx.doi.org/10.1093/bioinformatics/btu861 |