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Unusual Presentation of Testicular Cancer with Tumor Thrombus Extending to the Inferior Vena Cava
A 45-year-old man with a left testis tumor with a 25 mm para-aortic lymph node swelling, multiple bilateral pulmonary metastases, bilateral pulmonary embolism, and inferior vena cava (IVC) thrombus underwent a radical orchidectomy in our institution. The thrombus extended from the left gonadal vein...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426900/ https://www.ncbi.nlm.nih.gov/pubmed/26000192 http://dx.doi.org/10.1155/2015/160560 |
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author | Dusaud, Marie Bayoud, Younes Desfemmes, François-Régis Molimard, Benoît Durand, Xavier |
author_facet | Dusaud, Marie Bayoud, Younes Desfemmes, François-Régis Molimard, Benoît Durand, Xavier |
author_sort | Dusaud, Marie |
collection | PubMed |
description | A 45-year-old man with a left testis tumor with a 25 mm para-aortic lymph node swelling, multiple bilateral pulmonary metastases, bilateral pulmonary embolism, and inferior vena cava (IVC) thrombus underwent a radical orchidectomy in our institution. The thrombus extended from the left gonadal vein to the left renal vein to the IVC. The fluorine-18 fluorodeoxyglucose (f-FDG) positron emission tomography (PET) computerized tomography (CT) demonstrated a hypermetabolic focus in the retroperitoneum and in the IVC thrombus. Before orchidectomy only lactate dehydrogenase (LDH) was high but all the serum tumor markers increased postoperatively. The tumor was staged pT1N2M1aS1, which was an intermediate prognosis, based on the International Germ Cell Cancer Collaborative Group consensus (IGCCCG). After 4 courses of bleomycin, etoposide, and cisplatin (BEP) chemotherapy the patient's tumor markers normalized and the thrombus disappeared. There was only one residual retroperitoneal lymph node M1. Retroperitoneal lymph node dissection was performed. The pathological examination revealed only necrotic tissues. The patient has been disease-free since surgery. |
format | Online Article Text |
id | pubmed-4426900 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-44269002015-05-21 Unusual Presentation of Testicular Cancer with Tumor Thrombus Extending to the Inferior Vena Cava Dusaud, Marie Bayoud, Younes Desfemmes, François-Régis Molimard, Benoît Durand, Xavier Case Rep Urol Case Report A 45-year-old man with a left testis tumor with a 25 mm para-aortic lymph node swelling, multiple bilateral pulmonary metastases, bilateral pulmonary embolism, and inferior vena cava (IVC) thrombus underwent a radical orchidectomy in our institution. The thrombus extended from the left gonadal vein to the left renal vein to the IVC. The fluorine-18 fluorodeoxyglucose (f-FDG) positron emission tomography (PET) computerized tomography (CT) demonstrated a hypermetabolic focus in the retroperitoneum and in the IVC thrombus. Before orchidectomy only lactate dehydrogenase (LDH) was high but all the serum tumor markers increased postoperatively. The tumor was staged pT1N2M1aS1, which was an intermediate prognosis, based on the International Germ Cell Cancer Collaborative Group consensus (IGCCCG). After 4 courses of bleomycin, etoposide, and cisplatin (BEP) chemotherapy the patient's tumor markers normalized and the thrombus disappeared. There was only one residual retroperitoneal lymph node M1. Retroperitoneal lymph node dissection was performed. The pathological examination revealed only necrotic tissues. The patient has been disease-free since surgery. Hindawi Publishing Corporation 2015 2015-04-27 /pmc/articles/PMC4426900/ /pubmed/26000192 http://dx.doi.org/10.1155/2015/160560 Text en Copyright © 2015 Marie Dusaud et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Dusaud, Marie Bayoud, Younes Desfemmes, François-Régis Molimard, Benoît Durand, Xavier Unusual Presentation of Testicular Cancer with Tumor Thrombus Extending to the Inferior Vena Cava |
title | Unusual Presentation of Testicular Cancer with Tumor Thrombus Extending to the Inferior Vena Cava |
title_full | Unusual Presentation of Testicular Cancer with Tumor Thrombus Extending to the Inferior Vena Cava |
title_fullStr | Unusual Presentation of Testicular Cancer with Tumor Thrombus Extending to the Inferior Vena Cava |
title_full_unstemmed | Unusual Presentation of Testicular Cancer with Tumor Thrombus Extending to the Inferior Vena Cava |
title_short | Unusual Presentation of Testicular Cancer with Tumor Thrombus Extending to the Inferior Vena Cava |
title_sort | unusual presentation of testicular cancer with tumor thrombus extending to the inferior vena cava |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426900/ https://www.ncbi.nlm.nih.gov/pubmed/26000192 http://dx.doi.org/10.1155/2015/160560 |
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