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Granulin, a novel STAT3-interacting protein, enhances STAT3 transcriptional function and correlates with poorer prognosis in breast cancer

Since the neoplastic phenotype of a cell is largely driven by aberrant gene expression patterns, increasing attention has been focused on transcription factors that regulate critical mediators of tumorigenesis such as signal transducer and activator of transcription 3 (STAT3). As proteins that inter...

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Detalles Bibliográficos
Autores principales: Yeh, Jennifer E., Kreimer, Simion, Walker, Sarah R., Emori, Megan M., Krystal, Hannah, Richardson, Andrea, Ivanov, Alexander R., Frank, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426952/
https://www.ncbi.nlm.nih.gov/pubmed/26000098