Three Patients Needing High Doses of Valproic Acid to Get Therapeutic Concentrations

Valproic acid (VPA) can autoinduce its own metabolism. Cases requiring VPA doses >4000 mg/day to obtain therapeutic plasma concentrations, such as these 3 cases, have never been published. Case 1 received VPA for seizures and schizophrenia and had >50 VPA concentrations in 4 years. A high dose...

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Detalles Bibliográficos
Autores principales: Jackson, James, McCollum, Betsy, Ognibene, Judy, Diaz, Francisco J., de Leon, Jose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427013/
https://www.ncbi.nlm.nih.gov/pubmed/26000191
http://dx.doi.org/10.1155/2015/542862

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427013/
https://www.ncbi.nlm.nih.gov/pubmed/26000191
http://dx.doi.org/10.1155/2015/542862

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