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The Role of p21 in Apoptosis, Proliferation, Cell Cycle Arrest, and Antioxidant Activity in UVB-Irradiated Human HaCaT Keratinocytes

BACKGROUND: Skin cancer is the most common cancer in the United States, and ultraviolet B (UVB) radiation-induced DNA damage is the major environmental factor underlying skin cancer development. p21, a p53-inducible protein, plays a key role in the cellular response to UVB-induced DNA damage. MATERI...

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Detalles Bibliográficos
Autores principales: Chen, Aijun, Huang, Xin, Xue, Zhenan, Cao, Di, Huang, Kun, Chen, Jin, Pan, Yun, Gao, Yongliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427023/
https://www.ncbi.nlm.nih.gov/pubmed/25925725
http://dx.doi.org/10.12659/MSMBR.893608

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