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Cervical cancer screening and treatment of cervical intraepithelial neoplasia in female sex workers using “screen and treat” approach
OBJECTIVE: Female sex workers (FSWs) are at an increased risk of human immunodeficiency virus (HIV) as well as human papillomavirus (HPV) infections and thus have an increased risk of cervical intraepithelial neoplasia (CIN) and cervical cancer. We evaluated the feasibility of “screen and treat appr...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427081/ https://www.ncbi.nlm.nih.gov/pubmed/25999765 http://dx.doi.org/10.2147/IJWH.S80624 |
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author | Joshi, Smita Kulkarni, Vinay Darak, Trupti Mahajan, Uma Srivastava, Yogesh Gupta, Sanjay Krishnan, Sumitra Mandolkar, Mahesh Bharti, Alok Chandra |
author_facet | Joshi, Smita Kulkarni, Vinay Darak, Trupti Mahajan, Uma Srivastava, Yogesh Gupta, Sanjay Krishnan, Sumitra Mandolkar, Mahesh Bharti, Alok Chandra |
author_sort | Joshi, Smita |
collection | PubMed |
description | OBJECTIVE: Female sex workers (FSWs) are at an increased risk of human immunodeficiency virus (HIV) as well as human papillomavirus (HPV) infections and thus have an increased risk of cervical intraepithelial neoplasia (CIN) and cervical cancer. We evaluated the feasibility of “screen and treat approach” for cervical cancer prevention and the performance of different screening tests among FSWs. METHODS: Women were screened using cytology, VIA (visual inspection with acetic acid), and VILI (visual inspection with Lugol’s iodine) and underwent colposcopy, biopsy, and immediate treatment using cold coagulation, if indicated, at the same visit. RESULTS: We screened 300 FSWs of whom 200 (66.67%) were HIV uninfected and 100 (33.34%) were HIV infected. The overall prevalence of CIN 2–3 lesions was 4.7%. But all women with CIN 2–3 lesions were HIV infected, and thus the prevalence of CIN 2–3 lesions in HIV-infected FSWs was 14/100 (14%, 95% confidence interval: 7.2–20.8). All of them screened positive by all three screening tests. Cold coagulation was well tolerated, with no appreciable side effects. CONCLUSION: Cervical cancer prevention by “screen and treat” approach using VIA, followed by ablative treatment, in this high-risk group of women is feasible and can be implemented through various targeted intervention programs. |
format | Online Article Text |
id | pubmed-4427081 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Dove Medical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-44270812015-05-21 Cervical cancer screening and treatment of cervical intraepithelial neoplasia in female sex workers using “screen and treat” approach Joshi, Smita Kulkarni, Vinay Darak, Trupti Mahajan, Uma Srivastava, Yogesh Gupta, Sanjay Krishnan, Sumitra Mandolkar, Mahesh Bharti, Alok Chandra Int J Womens Health Original Research OBJECTIVE: Female sex workers (FSWs) are at an increased risk of human immunodeficiency virus (HIV) as well as human papillomavirus (HPV) infections and thus have an increased risk of cervical intraepithelial neoplasia (CIN) and cervical cancer. We evaluated the feasibility of “screen and treat approach” for cervical cancer prevention and the performance of different screening tests among FSWs. METHODS: Women were screened using cytology, VIA (visual inspection with acetic acid), and VILI (visual inspection with Lugol’s iodine) and underwent colposcopy, biopsy, and immediate treatment using cold coagulation, if indicated, at the same visit. RESULTS: We screened 300 FSWs of whom 200 (66.67%) were HIV uninfected and 100 (33.34%) were HIV infected. The overall prevalence of CIN 2–3 lesions was 4.7%. But all women with CIN 2–3 lesions were HIV infected, and thus the prevalence of CIN 2–3 lesions in HIV-infected FSWs was 14/100 (14%, 95% confidence interval: 7.2–20.8). All of them screened positive by all three screening tests. Cold coagulation was well tolerated, with no appreciable side effects. CONCLUSION: Cervical cancer prevention by “screen and treat” approach using VIA, followed by ablative treatment, in this high-risk group of women is feasible and can be implemented through various targeted intervention programs. Dove Medical Press 2015-05-04 /pmc/articles/PMC4427081/ /pubmed/25999765 http://dx.doi.org/10.2147/IJWH.S80624 Text en © 2015 Joshi et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. |
spellingShingle | Original Research Joshi, Smita Kulkarni, Vinay Darak, Trupti Mahajan, Uma Srivastava, Yogesh Gupta, Sanjay Krishnan, Sumitra Mandolkar, Mahesh Bharti, Alok Chandra Cervical cancer screening and treatment of cervical intraepithelial neoplasia in female sex workers using “screen and treat” approach |
title | Cervical cancer screening and treatment of cervical intraepithelial neoplasia in female sex workers using “screen and treat” approach |
title_full | Cervical cancer screening and treatment of cervical intraepithelial neoplasia in female sex workers using “screen and treat” approach |
title_fullStr | Cervical cancer screening and treatment of cervical intraepithelial neoplasia in female sex workers using “screen and treat” approach |
title_full_unstemmed | Cervical cancer screening and treatment of cervical intraepithelial neoplasia in female sex workers using “screen and treat” approach |
title_short | Cervical cancer screening and treatment of cervical intraepithelial neoplasia in female sex workers using “screen and treat” approach |
title_sort | cervical cancer screening and treatment of cervical intraepithelial neoplasia in female sex workers using “screen and treat” approach |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427081/ https://www.ncbi.nlm.nih.gov/pubmed/25999765 http://dx.doi.org/10.2147/IJWH.S80624 |
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