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Deficient copper concentrations in dried-defatted hepatic tissue from ob/ob mice: A potential model for study of defective copper regulation in metabolic liver disease

Ob/ob mice provide an animal model for non-alcoholic fatty liver disease/non-alcoholic steatohepatitis (NAFLD/NASH) in patients with obesity and type-2 diabetes. Low liver copper has been linked to hepatic lipid build-up (steatosis) in animals with systemic copper deficiency caused by low-copper die...

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Detalles Bibliográficos
Autores principales:	Church, Stephanie J., Begley, Paul, Kureishy, Nina, McHarg, Selina, Bishop, Paul N., Bechtold, David A., Unwin, Richard D., Cooper, Garth J.S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Academic Press 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427106/ https://www.ncbi.nlm.nih.gov/pubmed/25797622 http://dx.doi.org/10.1016/j.bbrc.2015.03.067

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