Cargando…
Chaperone-Mediated Autophagy Targets IFNAR1 for Lysosomal Degradation in Free Fatty Acid Treated HCV Cell Culture
BACKGROUND: Hepatic steatosis is a risk factor for both liver disease progression and an impaired response to interferon alpha (IFN-α)-based combination therapy in chronic hepatitis C virus (HCV) infection. Previously, we reported that free fatty acid (FFA)-treated HCV cell culture induces hepatocel...
Autores principales: | Kurt, Ramazan, Chandra, Partha K., Aboulnasr, Fatma, Panigrahi, Rajesh, Ferraris, Pauline, Aydin, Yucel, Reiss, Krzysztof, Wu, Tong, Balart, Luis A., Dash, Srikanta |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427131/ https://www.ncbi.nlm.nih.gov/pubmed/25961570 http://dx.doi.org/10.1371/journal.pone.0125962 |
Ejemplares similares
-
IFN-λ Inhibits MiR-122 Transcription through a Stat3-HNF4α Inflammatory Feedback Loop in an IFN-α Resistant HCV Cell Culture System
por: Aboulnasr, Fatma, et al.
Publicado: (2015) -
Interferon and Ribavirin Combination Treatment Synergistically Inhibit HCV Internal Ribosome Entry Site Mediated Translation at the Level of Polyribosome Formation
por: Panigrahi, Rajesh, et al.
Publicado: (2013) -
Chaperone-Mediated Autophagy in the Liver: Good or Bad?
por: Dash, Srikanta, et al.
Publicado: (2019) -
Hepatitis C Virus Infection Induces Autophagy as a Prosurvival Mechanism to Alleviate Hepatic ER-Stress Response
por: Dash, Srikanta, et al.
Publicado: (2016) -
Impaired Expression of Type I and Type II Interferon Receptors in HCV-Associated Chronic Liver Disease and Liver Cirrhosis
por: Chandra, Partha K., et al.
Publicado: (2014)