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Structural and functional analysis of betaine aldehyde dehydrogenase from Staphylococcus aureus

When exposed to high osmolarity, methicillin-resistant Staphylococcus aureus (MRSA) restores its growth and establishes a new steady state by accumulating the osmoprotectant metabolite betaine. Effective osmoregulation has also been implicated in the acquirement of a profound antibiotic resistance b...

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Detalles Bibliográficos
Autores principales: Halavaty, Andrei S., Rich, Rebecca L., Chen, Chao, Joo, Jeong Chan, Minasov, George, Dubrovska, Ievgeniia, Winsor, James R., Myszka, David G., Duban, Mark, Shuvalova, Ludmilla, Yakunin, Alexander F., Anderson, Wayne F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427200/
https://www.ncbi.nlm.nih.gov/pubmed/25945581
http://dx.doi.org/10.1107/S1399004715004228