Altered KLOTHO and NF-κB-TNF-α Signaling Are Correlated with Nephrectomy-Induced Cognitive Impairment in Rats

Renal insufficiency can have a negative impact on cognitive function. Neuroinflammation and changes in klotho levels associate with chronic kidney disease (CKD) and may play a role in the development of cognitive impairment (CI). The present study evaluates the correlation of cognitive deficits with...

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Detalles Bibliográficos
Autores principales: Degaspari, Sabrina, Tzanno-Martins, Carmen Branco, Fujihara, Clarice Kazue, Zatz, Roberto, Branco-Martins, João Paulo, Viel, Tania Araujo, Buck, Hudson de Souza, Orellana, Ana Maria Marques, Böhmer, Ana Elisa, de Sá Lima, Larissa, Andreotti, Diana Zukas, Munhoz, Carolina Demarchi, Scavone, Cristoforo, Kawamoto, Elisa Mitiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427267/
https://www.ncbi.nlm.nih.gov/pubmed/25961830
http://dx.doi.org/10.1371/journal.pone.0125271

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