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Adjusting the frequency of mammography screening on the basis of genetic risk: Attitudes among women in the UK
PURPOSE: To explore public attitudes towards modifying frequency of mammography screening based on genetic risk. METHODS: Home-based interviews were carried out with a population-based sample of 942 women aged 18–74 years in the UK. Demographic characteristics and perceived breast cancer (BC) risk w...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427278/ https://www.ncbi.nlm.nih.gov/pubmed/25708717 http://dx.doi.org/10.1016/j.breast.2015.02.001 |
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author | Meisel, Susanne F. Pashayan, Nora Rahman, Belinda Side, Lucy Fraser, Lindsay Gessler, Sue Lanceley, Anne Wardle, Jane |
author_facet | Meisel, Susanne F. Pashayan, Nora Rahman, Belinda Side, Lucy Fraser, Lindsay Gessler, Sue Lanceley, Anne Wardle, Jane |
author_sort | Meisel, Susanne F. |
collection | PubMed |
description | PURPOSE: To explore public attitudes towards modifying frequency of mammography screening based on genetic risk. METHODS: Home-based interviews were carried out with a population-based sample of 942 women aged 18–74 years in the UK. Demographic characteristics and perceived breast cancer (BC) risk were examined as predictors of support for risk-stratified BC screening and of the acceptability of raised or lowered screening frequency based on genetic risk, using multivariate logistic regression. RESULTS: Over two-thirds of respondents (65.8%) supported the idea of varying screening frequency on the basis of genetic risk. The majority (85.4%) were willing to have more frequent breast screening if they were found to be at higher risk, but fewer (58.8%) were willing to have less frequent screening if at lower risk (t (956) = 15.6, p < 0.001). Ethnic minority status was associated with less acceptability of more frequent screening (OR = 0.40, 95% CI = 0.21–0.74), but there were no other significant demographic correlates. Higher perceived risk of BC was associated with greater acceptability of more frequent screening (OR = 1.71, 95%CI = 1.27–2.30). CONCLUSION: Women were positive about adjusting the frequency of mammography screening in line with personal genetic risk, but it will be important to develop effective communication materials to minimise resistance to reducing screening frequency for those at lower genetic risk. |
format | Online Article Text |
id | pubmed-4427278 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-44272782015-06-01 Adjusting the frequency of mammography screening on the basis of genetic risk: Attitudes among women in the UK Meisel, Susanne F. Pashayan, Nora Rahman, Belinda Side, Lucy Fraser, Lindsay Gessler, Sue Lanceley, Anne Wardle, Jane Breast Orginal Article PURPOSE: To explore public attitudes towards modifying frequency of mammography screening based on genetic risk. METHODS: Home-based interviews were carried out with a population-based sample of 942 women aged 18–74 years in the UK. Demographic characteristics and perceived breast cancer (BC) risk were examined as predictors of support for risk-stratified BC screening and of the acceptability of raised or lowered screening frequency based on genetic risk, using multivariate logistic regression. RESULTS: Over two-thirds of respondents (65.8%) supported the idea of varying screening frequency on the basis of genetic risk. The majority (85.4%) were willing to have more frequent breast screening if they were found to be at higher risk, but fewer (58.8%) were willing to have less frequent screening if at lower risk (t (956) = 15.6, p < 0.001). Ethnic minority status was associated with less acceptability of more frequent screening (OR = 0.40, 95% CI = 0.21–0.74), but there were no other significant demographic correlates. Higher perceived risk of BC was associated with greater acceptability of more frequent screening (OR = 1.71, 95%CI = 1.27–2.30). CONCLUSION: Women were positive about adjusting the frequency of mammography screening in line with personal genetic risk, but it will be important to develop effective communication materials to minimise resistance to reducing screening frequency for those at lower genetic risk. Elsevier 2015-06 /pmc/articles/PMC4427278/ /pubmed/25708717 http://dx.doi.org/10.1016/j.breast.2015.02.001 Text en © 2015 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Orginal Article Meisel, Susanne F. Pashayan, Nora Rahman, Belinda Side, Lucy Fraser, Lindsay Gessler, Sue Lanceley, Anne Wardle, Jane Adjusting the frequency of mammography screening on the basis of genetic risk: Attitudes among women in the UK |
title | Adjusting the frequency of mammography screening on the basis of genetic risk: Attitudes among women in the UK |
title_full | Adjusting the frequency of mammography screening on the basis of genetic risk: Attitudes among women in the UK |
title_fullStr | Adjusting the frequency of mammography screening on the basis of genetic risk: Attitudes among women in the UK |
title_full_unstemmed | Adjusting the frequency of mammography screening on the basis of genetic risk: Attitudes among women in the UK |
title_short | Adjusting the frequency of mammography screening on the basis of genetic risk: Attitudes among women in the UK |
title_sort | adjusting the frequency of mammography screening on the basis of genetic risk: attitudes among women in the uk |
topic | Orginal Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427278/ https://www.ncbi.nlm.nih.gov/pubmed/25708717 http://dx.doi.org/10.1016/j.breast.2015.02.001 |
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