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Loss of Bace1 in Mice Does Not Alter the Severity of Caerulein Induced Pancreatitis

CONTEXT: Beta-site alpha-amyloid protein cleaving enzyme1 (BACE1) plays a key role in the pathogenesis of Alzheimer’s disease. Additional to its moderate expression in the brain, high levels of BACE1 mRNA were found in the pancreas. Murine Bace1 has been immunohistochemicaly detected at the apical p...

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Detalles Bibliográficos
Autores principales: Heindl, Mario, Tuennemann, Jan, Sommerer, Ines, Mössner, Joachim, Hoffmeister, Albrecht
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427297/
https://www.ncbi.nlm.nih.gov/pubmed/25961820
http://dx.doi.org/10.1371/journal.pone.0125556