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Acute Glucagon Induces Postprandial Peripheral Insulin Resistance

Glucagon levels are often moderately elevated in diabetes. It is known that glucagon leads to a decrease in hepatic glutathione (GSH) synthesis that in turn is associated with decreased postprandial insulin sensitivity. Given that cAMP pathway controls GSH levels we tested whether insulin sensitivit...

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Detalles Bibliográficos
Autores principales: Patarrão, Rita S., Lautt, W. Wayne, Macedo, M. Paula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427479/
https://www.ncbi.nlm.nih.gov/pubmed/25961284
http://dx.doi.org/10.1371/journal.pone.0127221