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Numerical Modeling of Intraventricular Flow during Diastole after Implantation of BMHV

This work presents a numerical simulation of intraventricular flow after the implantation of a bileaflet mechanical heart valve at the mitral position. The left ventricle was simplified conceptually as a truncated prolate spheroid and its motion was prescribed based on that of a healthy subject. The...

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Autores principales: Su, Boyang, Kabinejadian, Foad, Phang, Hui Qun, Kumar, Gideon Praveen, Cui, Fangsen, Kim, Sangho, Tan, Ru San, Hon, Jimmy Kim Fatt, Allen, John Carson, Leo, Hwa Liang, Zhong, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427484/
https://www.ncbi.nlm.nih.gov/pubmed/25961285
http://dx.doi.org/10.1371/journal.pone.0126315
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author Su, Boyang
Kabinejadian, Foad
Phang, Hui Qun
Kumar, Gideon Praveen
Cui, Fangsen
Kim, Sangho
Tan, Ru San
Hon, Jimmy Kim Fatt
Allen, John Carson
Leo, Hwa Liang
Zhong, Liang
author_facet Su, Boyang
Kabinejadian, Foad
Phang, Hui Qun
Kumar, Gideon Praveen
Cui, Fangsen
Kim, Sangho
Tan, Ru San
Hon, Jimmy Kim Fatt
Allen, John Carson
Leo, Hwa Liang
Zhong, Liang
author_sort Su, Boyang
collection PubMed
description This work presents a numerical simulation of intraventricular flow after the implantation of a bileaflet mechanical heart valve at the mitral position. The left ventricle was simplified conceptually as a truncated prolate spheroid and its motion was prescribed based on that of a healthy subject. The rigid leaflet rotation was driven by the transmitral flow and hence the leaflet dynamics were solved using fluid-structure interaction approach. The simulation results showed that the bileaflet mechanical heart valve at the mitral position behaved similarly to that at the aortic position. Sudden area expansion near the aortic root initiated a clockwise anterior vortex, and the continuous injection of flow through the orifice resulted in further growth of the anterior vortex during diastole, which dominated the intraventricular flow. This flow feature is beneficial to preserving the flow momentum and redirecting the blood flow towards the aortic valve. To the best of our knowledge, this is the first attempt to numerically model intraventricular flow with the mechanical heart valve incorporated at the mitral position using a fluid-structure interaction approach. This study facilitates future patient-specific studies.
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spelling pubmed-44274842015-05-21 Numerical Modeling of Intraventricular Flow during Diastole after Implantation of BMHV Su, Boyang Kabinejadian, Foad Phang, Hui Qun Kumar, Gideon Praveen Cui, Fangsen Kim, Sangho Tan, Ru San Hon, Jimmy Kim Fatt Allen, John Carson Leo, Hwa Liang Zhong, Liang PLoS One Research Article This work presents a numerical simulation of intraventricular flow after the implantation of a bileaflet mechanical heart valve at the mitral position. The left ventricle was simplified conceptually as a truncated prolate spheroid and its motion was prescribed based on that of a healthy subject. The rigid leaflet rotation was driven by the transmitral flow and hence the leaflet dynamics were solved using fluid-structure interaction approach. The simulation results showed that the bileaflet mechanical heart valve at the mitral position behaved similarly to that at the aortic position. Sudden area expansion near the aortic root initiated a clockwise anterior vortex, and the continuous injection of flow through the orifice resulted in further growth of the anterior vortex during diastole, which dominated the intraventricular flow. This flow feature is beneficial to preserving the flow momentum and redirecting the blood flow towards the aortic valve. To the best of our knowledge, this is the first attempt to numerically model intraventricular flow with the mechanical heart valve incorporated at the mitral position using a fluid-structure interaction approach. This study facilitates future patient-specific studies. Public Library of Science 2015-05-11 /pmc/articles/PMC4427484/ /pubmed/25961285 http://dx.doi.org/10.1371/journal.pone.0126315 Text en © 2015 Su et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Su, Boyang
Kabinejadian, Foad
Phang, Hui Qun
Kumar, Gideon Praveen
Cui, Fangsen
Kim, Sangho
Tan, Ru San
Hon, Jimmy Kim Fatt
Allen, John Carson
Leo, Hwa Liang
Zhong, Liang
Numerical Modeling of Intraventricular Flow during Diastole after Implantation of BMHV
title Numerical Modeling of Intraventricular Flow during Diastole after Implantation of BMHV
title_full Numerical Modeling of Intraventricular Flow during Diastole after Implantation of BMHV
title_fullStr Numerical Modeling of Intraventricular Flow during Diastole after Implantation of BMHV
title_full_unstemmed Numerical Modeling of Intraventricular Flow during Diastole after Implantation of BMHV
title_short Numerical Modeling of Intraventricular Flow during Diastole after Implantation of BMHV
title_sort numerical modeling of intraventricular flow during diastole after implantation of bmhv
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427484/
https://www.ncbi.nlm.nih.gov/pubmed/25961285
http://dx.doi.org/10.1371/journal.pone.0126315
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