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La FAM fatale: USP9X in development and disease
Deubiquitylating enzymes (DUBs), act downstream of ubiquitylation. As such, these post-post-translational modifiers function as the final arbitrators of a protein substrate’s ubiquitylation status, thus regulating its fate. In most instances, DUBs moderate the absolute level of a substrate, its loca...
Autores principales: | Murtaza, Mariyam, Jolly, Lachlan A., Gecz, Jozef, Wood, Stephen A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Basel
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427618/ https://www.ncbi.nlm.nih.gov/pubmed/25672900 http://dx.doi.org/10.1007/s00018-015-1851-0 |
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