Cargando…

The synaptotagmin juxtamembrane domain is involved in neuroexocytosis

Synaptotagmin is a synaptic vesicle membrane protein which changes conformation upon Ca(2+) binding and triggers the fast neuroexocytosis that takes place at synapses. We have synthesized a series of peptides corresponding to the sequence of the cytosolic juxtamembrane domain of synaptotagmin, which...

Descripción completa

Detalles Bibliográficos
Autores principales:	Caccin, Paola, Scorzeto, Michele, Damiano, Nunzio, Marin, Oriano, Megighian, Aram, Montecucco, Cesare
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427626/ https://www.ncbi.nlm.nih.gov/pubmed/25973365 http://dx.doi.org/10.1016/j.fob.2015.04.013

Ejemplares similares

Snake and Spider Toxins Induce a Rapid Recovery of Function of Botulinum Neurotoxin Paralysed Neuromuscular Junction
por: Duregotti, Elisa, et al.
Publicado: (2015)

Characterization of Ginkgo biloba Leaf Flavonoids as Neuroexocytosis Regulators
por: Ban, Choongjin, et al.
Publicado: (2020)

Electrophysiological Characterization of the Antarease Metalloprotease from Tityus serrulatus Venom
por: Zornetta, Irene, et al.
Publicado: (2017)

Synaptotagmin 1 oligomerization via the juxtamembrane linker regulates spontaneous and evoked neurotransmitter release
por: Courtney, Kevin C., et al.
Publicado: (2021)

The first non Clostridial botulinum-like toxin cleaves VAMP within the juxtamembrane domain
por: Zornetta, Irene, et al.
Publicado: (2016)

The juxtamembrane linker of synaptotagmin 1 regulates Ca(2+) binding via liquid-liquid phase separation
por: Mehta, Nikunj, et al.
Publicado: (2023)

Consequences of replacing EGFR juxtamembrane domain with an unstructured sequence
por: He, Lijuan, et al.
Publicado: (2012)

Autoinhibition of the Ron receptor tyrosine kinase by the juxtamembrane domain
por: Wang, Xin, et al.
Publicado: (2014)

Glial TDP-43 regulates axon wrapping, GluRIIA clustering and fly motility by autonomous and non-autonomous mechanisms
por: Romano, Giulia, et al.
Publicado: (2015)

Fusion with wild-type SNARE domains is controlled by juxtamembrane domains, transmembrane anchors, and Sec17
por: Orr, Amy, et al.
Publicado: (2022)

Envenomations by Bothrops and Crotalus Snakes Induce the Release of Mitochondrial Alarmins
por: Zornetta, Irene, et al.
Publicado: (2012)

c-Met Mutational Analysis in the Sema and Juxtamembrane Domains in Small-Cell-Lung-Cancer
por: de Aguirre, Itziar, et al.
Publicado: (2006)

The juxtamembrane domain of the E-cadherin cytoplasmic tail contributes to its interaction with Myosin VI
por: Mangold, Sabine, et al.
Publicado: (2012)

Melatonin promotes regeneration of injured motor axons via MT(1) receptors
por: Stazi, Marco, et al.
Publicado: (2020)

Insights into membrane association of the SMP domain of extended synaptotagmin
por: Wang, Yunyun, et al.
Publicado: (2023)

Requirement of the juxtamembrane domain of the cadherin cytoplasmic tail for morphogenetic cell rearrangement during myotome development
por: Horikawa, Kazuki, et al.
Publicado: (2001)

Nuclear localization of orphan receptor protein kinase (Ror1) is mediated through the juxtamembrane domain
por: Tseng, Hsiao-Chun, et al.
Publicado: (2010)

A Potential Peptide Therapeutic Derived from the Juxtamembrane Domain of the Epidermal Growth Factor Receptor
por: Boran, Aislyn D. W., et al.
Publicado: (2012)

Clinical and molecular features of FLT3 juxtamembrane domain missense mutations in acute myeloid leukaemia
por: Jensen, Christopher E., et al.
Publicado: (2022)

An agonist of the CXCR4 receptor accelerates the recovery from the peripheral neuroparalysis induced by Taipan snake envenomation
por: Stazi, Marco, et al.
Publicado: (2020)

Schwann cells are activated by ATP released from neurons in an in vitro cellular model of Miller Fisher syndrome
por: Rodella, Umberto, et al.
Publicado: (2017)

A Role for the V0 Sector of the V-ATPase in Neuroexocytosis: Exogenous V0d Blocks Complexin and SNARE Interactions with V0c
por: Lévêque, Christian, et al.
Publicado: (2023)

Synaptotagmins are trafficked to distinct subcellular domains including the postsynaptic compartment
por: Adolfsen, Bill, et al.
Publicado: (2004)

Temperature-sensitive gating of TRPV1 channel as probed by atomistic simulations of its trans- and juxtamembrane domains
por: Chugunov, Anton O., et al.
Publicado: (2016)

Transmembrane and Juxtamembrane Structure of αL Integrin in Bicelles
por: Surya, Wahyu, et al.
Publicado: (2013)

A CXCR4 receptor agonist strongly stimulates axonal regeneration after damage
por: Zanetti, Giulia, et al.
Publicado: (2019)

ATP Released by Injured Neurons Activates Schwann Cells
por: Negro, Samuele, et al.
Publicado: (2016)

Cutaneous mastocytosis with a mutation in the juxtamembrane domain of c-kit in a young laboratory beagle dog
por: Kato, Yuki, et al.
Publicado: (2015)

The juxtamembrane and carboxy-terminal domains of Arabidopsis PRK2 are critical for ROP-induced growth in pollen tubes
por: Zhao, Xin-Ying, et al.
Publicado: (2013)

Deletion and deletion/insertion mutations in the juxtamembrane domain of the FLT3 gene in adult acute myeloid leukemia
por: Deeb, Kristin K., et al.
Publicado: (2014)

Latrotoxin-Induced Neuromuscular Junction Degeneration Reveals Urocortin 2 as a Critical Contributor to Motor Axon Terminal Regeneration
por: D’Este, Giorgia, et al.
Publicado: (2022)

Syntaxin-1A modulates vesicle fusion in mammalian neurons via juxtamembrane domain dependent palmitoylation of its transmembrane domain
por: Vardar, Gülçin, et al.
Publicado: (2022)

Feedback control of ErbB2 via ERK-mediated phosphorylation of a conserved threonine in the juxtamembrane domain
por: Kawasaki, Yuki, et al.
Publicado: (2016)

The architecture of transmembrane and cytoplasmic juxtamembrane regions of Toll-like receptors
por: Kornilov, F. D., et al.
Publicado: (2023)

A Role for the Juxtamembrane Cytoplasm in the Molecular Dynamics of Focal Adhesions
por: Wolfenson, Haguy, et al.
Publicado: (2009)

Recovery from the Neuroparalysis Caused by the Micrurus nigrocinctus Venom Is Accelerated by an Agonist of the CXCR4 Receptor
por: Stazi, Marco, et al.
Publicado: (2022)

Progressing Vulvar Melanoma Caused by Instability in cKIT Juxtamembrane Domain: A Case Report and Review of Literature
por: Englert-Golon, Monika, et al.
Publicado: (2022)

Ring-like oligomers of Synaptotagmins and related C2 domain proteins
por: Zanetti, Maria N, et al.
Publicado: (2016)

Nerve-dependent distribution of subsynaptic type 1 inositol 1,4,5-trisphosphate receptor at the neuromuscular junction
por: Volpe, Pompeo, et al.
Publicado: (2022)

Conserved regulatory motifs in the juxtamembrane domain and kinase N-lobe revealed through deep mutational scanning of the MET receptor tyrosine kinase domain
por: Estevam, Gabriella O., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_s4qq3hgt8b2o7j3gvkcnveqvp4