Cargando…

Solution structures of the DNA-binding domains of immune-related zinc-finger protein ZFAT

ZFAT is a transcriptional regulator, containing eighteen C(2)H(2)-type zinc-fingers and one AT-hook, involved in autoimmune thyroid disease, apoptosis, and immune-related cell survival. We determined the solution structures of the thirteen individual ZFAT zinc-fingers (ZF) and the tandemly arrayed z...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tochio, Naoya, Umehara, Takashi, Nakabayashi, Kazuhiko, Yoneyama, Misao, Tsuda, Kengo, Shirouzu, Mikako, Koshiba, Seizo, Watanabe, Satoru, Kigawa, Takanori, Sasazuki, Takehiko, Shirasawa, Senji, Yokoyama, Shigeyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Netherlands 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427657/ https://www.ncbi.nlm.nih.gov/pubmed/25801860 http://dx.doi.org/10.1007/s10969-015-9196-3

Ejemplares similares

ZFAT is a critical molecule for cell survival in mouse embryonic fibroblasts
por: Doi, Keiko, et al.
Publicado: (2010)

ZFAT is essential for endothelial cell assembly and the branch point formation of capillary-like structures in an angiogenesis model
por: Yoshida, Yasuhiro, et al.
Publicado: (2010)

CENP-B promotes the centromeric localization of ZFAT to control transcription of noncoding RNA
por: Ishikura, Shuhei, et al.
Publicado: (2021)

The transcriptional regulator Zfat is essential for maintenance and differentiation of the adipocytes
por: Ishikura, Shuhei, et al.
Publicado: (2021)

Zfat expression in ZsGreen reporter gene knock-in mice: Implications for a novel function of Zfat in definitive erythropoiesis
por: Tsunoda, Toshiyuki, et al.
Publicado: (2018)

ZFAT binds to centromeres to control noncoding RNA transcription through the KAT2B–H4K8ac–BRD4 axis
por: Ishikura, Shuhei, et al.
Publicado: (2020)

Zfat-Deficiency Results in a Loss of CD3ζ Phosphorylation with Dysregulation of ERK and Egr Activities Leading to Impaired Positive Selection
por: Ogawa, Masahiro, et al.
Publicado: (2013)

Solution structure of the first RNA recognition motif domain of human spliceosomal protein SF3b49 and its mode of interaction with a SF3b145 fragment
por: Kuwasako, Kanako, et al.
Publicado: (2016)

Death domain–associated protein DAXX regulates noncoding RNA transcription at the centromere through the transcription regulator ZFAT
por: Ishikura, Shuhei, et al.
Publicado: (2022)

Structural basis for the sequence-specific RNA-recognition mechanism of human CUG-BP1 RRM3
por: Tsuda, Kengo, et al.
Publicado: (2009)

Structural basis for the dual RNA-recognition modes of human Tra2-β RRM
por: Tsuda, Kengo, et al.
Publicado: (2011)

Intra- and inter-nucleosomal interactions of the histone H4 tail revealed with a human nucleosome core particle with genetically-incorporated H4 tetra-acetylation
por: Wakamori, Masatoshi, et al.
Publicado: (2015)

BRAF and RAS oncogenes regulate Rho GTPase pathways to mediate migration and invasion properties in human colon cancer cells: a comparative study
por: Makrodouli, Eleni, et al.
Publicado: (2011)

Amino-acid selective isotope labeling enables simultaneous overlapping signal decomposition and information extraction from NMR spectra
por: Kasai, Takuma, et al.
Publicado: (2020)

A novel 3′ splice site recognition by the two zinc fingers in the U2AF small subunit
por: Yoshida, Hisashi, et al.
Publicado: (2015)

Metabolic Alterations Caused by KRAS Mutations in Colorectal Cancer Contribute to Cell Adaptation to Glutamine Depletion by Upregulation of Asparagine Synthetase()()
por: Toda, Kosuke, et al.
Publicado: (2016)

Cell-permeable Carboxyl-terminal p27(Kip1) Peptide Exhibits Anti-tumor Activity by Inhibiting Pim-1 Kinase
por: Morishita, Daisuke, et al.
Publicado: (2011)

The RRM domain of poly(A)-specific ribonuclease has a noncanonical binding site for mRNA cap analog recognition
por: Nagata, Takashi, et al.
Publicado: (2008)

The zinc-binding region (ZBR) fragment of Emi2 can inhibit APC/C by targeting its association with the coactivator Cdc20 and UBE2C-mediated ubiquitylation
por: Shoji, Shisako, et al.
Publicado: (2014)

BRAF associated autophagy exploitation: BRAF and autophagy inhibitors synergise to efficiently overcome resistance of BRAF mutant colorectal cancer cells
por: Goulielmaki, Maria, et al.
Publicado: (2016)

Functional and structural basis of the nuclear localization signal in the ZIC3 zinc finger domain
por: Hatayama, Minoru, et al.
Publicado: (2008)

Altered Energy Homeostasis and Resistance to Diet-Induced Obesity in KRAP-Deficient Mice
por: Fujimoto, Takahiro, et al.
Publicado: (2009)

Activation of L-lactate oxidase by the formation of enzyme assemblies through liquid–liquid phase separation
por: Ura, Tomoto, et al.
Publicado: (2023)

Topological Analysis of MAPK Cascade for Kinetic ErbB Signaling
por: Nakakuki, Takashi, et al.
Publicado: (2008)

Dictyostelium IQGAP-related Protein Specifically Involved in the Completion of Cytokinesis
por: Adachi, Hiroyuki, et al.
Publicado: (1997)

Substrate Binding Switches the Conformation at the Lynchpin Site in the Substrate-Binding Domain of Human Hsp70 to Enable Allosteric Interdomain Communication
por: Umehara, Kohei, et al.
Publicado: (2018)

Investigating the Roles of the C-Terminal Domain of Plasmodium falciparum GyrA
por: Nagano, Soshichiro, et al.
Publicado: (2015)

ZFAT gene variant association with multiple sclerosis in the Arabian Gulf population: A genetic basis for gender-associated susceptibility
por: Bourguiba-Hachemi, Sonia, et al.
Publicado: (2016)

p120RasGAP Is a Mediator of Rho Pathway Activation and Tumorigenicity in the DLD1 Colorectal Cancer Cell Line
por: Organ, Shawna L., et al.
Publicado: (2014)

Identification of a Proline-Kinked Amphipathic α-Helix Downstream from the Methyltransferase Domain of a Potexvirus Replicase and Its Role in Virus Replication and Perinuclear Complex Formation
por: Komatsu, Ken, et al.
Publicado: (2021)

Content of intrinsic disorder influences the outcome of cell-free protein synthesis
por: Tokmakov, Alexander A., et al.
Publicado: (2015)

Molecular actions of two synthetic brassinosteroids, iso-carbaBL and 6-deoxoBL, which cause altered physiological activities between Arabidopsis and rice
por: Nakamura, Ayako, et al.
Publicado: (2017)

Cell-Free Protein Synthesis Using S30 Extracts from Escherichia coli RFzero Strains for Efficient Incorporation of Non-Natural Amino Acids into Proteins
por: Adachi, Jiro, et al.
Publicado: (2019)

Identification of KRAP-expressing cells and the functional relevance of KRAP to the subcellular localization of IP(3)R in the stomach and kidney
por: FUJIMOTO, TAKAHIRO, et al.
Publicado: (2012)

Impact of oncogenic driver mutations on feedback between the PI3K and MEK pathways in cancer cells
por: Yuen, Hiu-Fung, et al.
Publicado: (2012)

Structural basis for promoter specificity switching of RNA polymerase by a phage factor
por: Tagami, Shunsuke, et al.
Publicado: (2014)

Expression, purification, crystallization and preliminary X-ray diffraction analysis of galactokinase from Pyrococcus horikoshii. Erratum
por: Inagaki, Eiji, et al.
Publicado: (2006)

Elucidation of binding preferences of YEATS domains to site-specific acetylated nucleosome core particles
por: Kikuchi, Masaki, et al.
Publicado: (2022)

Priming of Anti-tumor Immune Mechanisms by Radiotherapy Is Augmented by Inhibition of Heat Shock Protein 90
por: Ernst, Anne, et al.
Publicado: (2020)

Cell-free synthesis of functional antibody fragments to provide a structural basis for antibody–antigen interaction
por: Matsuda, Takayoshi, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_cbfhg216f8bs5gklac3l8u4216