Increased proportions of CCR4(+) cells among peripheral blood CD4(+) cells and serum levels of allergen-specific IgE antibody in canine chronic rhinitis and bronchitis

Canine chronic rhinitis (CR) and bronchitis (CB) are suspected to be allergic diseases. The present study tested whether dogs diagnosed with CR or CB present an atopic predisposition based on the ratio of CC chemokine receptor 4 (CCR4)-positive cells among peripheral blood CD4-positive cells (CCR4/C...

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Autores principales: YAMAYA, Yoshiki, WATARI, Toshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2014
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427742/
https://www.ncbi.nlm.nih.gov/pubmed/25650058
http://dx.doi.org/10.1292/jvms.14-0338
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author YAMAYA, Yoshiki
WATARI, Toshihiro
author_facet YAMAYA, Yoshiki
WATARI, Toshihiro
author_sort YAMAYA, Yoshiki
collection PubMed
description Canine chronic rhinitis (CR) and bronchitis (CB) are suspected to be allergic diseases. The present study tested whether dogs diagnosed with CR or CB present an atopic predisposition based on the ratio of CC chemokine receptor 4 (CCR4)-positive cells among peripheral blood CD4-positive cells (CCR4/CD4) and the serum levels of allergen-specific IgE antibodies. We found that most dogs with CR and CB have a possibility of atopic predisposition, and macrolide therapy constitutes an alternative to corticosteroid therapy in controlling the clinical signs.
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spelling pubmed-44277422015-05-21 Increased proportions of CCR4(+) cells among peripheral blood CD4(+) cells and serum levels of allergen-specific IgE antibody in canine chronic rhinitis and bronchitis YAMAYA, Yoshiki WATARI, Toshihiro J Vet Med Sci Internal Medicine Canine chronic rhinitis (CR) and bronchitis (CB) are suspected to be allergic diseases. The present study tested whether dogs diagnosed with CR or CB present an atopic predisposition based on the ratio of CC chemokine receptor 4 (CCR4)-positive cells among peripheral blood CD4-positive cells (CCR4/CD4) and the serum levels of allergen-specific IgE antibodies. We found that most dogs with CR and CB have a possibility of atopic predisposition, and macrolide therapy constitutes an alternative to corticosteroid therapy in controlling the clinical signs. The Japanese Society of Veterinary Science 2014-12-19 2015-04 /pmc/articles/PMC4427742/ /pubmed/25650058 http://dx.doi.org/10.1292/jvms.14-0338 Text en ©2015 The Japanese Society of Veterinary Science http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License.
spellingShingle Internal Medicine
YAMAYA, Yoshiki
WATARI, Toshihiro
Increased proportions of CCR4(+) cells among peripheral blood CD4(+) cells and serum levels of allergen-specific IgE antibody in canine chronic rhinitis and bronchitis
title Increased proportions of CCR4(+) cells among peripheral blood CD4(+) cells and serum levels of allergen-specific IgE antibody in canine chronic rhinitis and bronchitis
title_full Increased proportions of CCR4(+) cells among peripheral blood CD4(+) cells and serum levels of allergen-specific IgE antibody in canine chronic rhinitis and bronchitis
title_fullStr Increased proportions of CCR4(+) cells among peripheral blood CD4(+) cells and serum levels of allergen-specific IgE antibody in canine chronic rhinitis and bronchitis
title_full_unstemmed Increased proportions of CCR4(+) cells among peripheral blood CD4(+) cells and serum levels of allergen-specific IgE antibody in canine chronic rhinitis and bronchitis
title_short Increased proportions of CCR4(+) cells among peripheral blood CD4(+) cells and serum levels of allergen-specific IgE antibody in canine chronic rhinitis and bronchitis
title_sort increased proportions of ccr4(+) cells among peripheral blood cd4(+) cells and serum levels of allergen-specific ige antibody in canine chronic rhinitis and bronchitis
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427742/
https://www.ncbi.nlm.nih.gov/pubmed/25650058
http://dx.doi.org/10.1292/jvms.14-0338
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AT wataritoshihiro increasedproportionsofccr4cellsamongperipheralbloodcd4cellsandserumlevelsofallergenspecificigeantibodyincaninechronicrhinitisandbronchitis

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