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A Survey on the Computational Approaches to Identify Drug Targets in the Postgenomic Era

Identifying drug targets plays essential roles in designing new drugs and combating diseases. Unfortunately, our current knowledge about drug targets is far from comprehensive. Screening drug targets in the lab is an expensive and time-consuming procedure. In the past decade, the accumulation of var...

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Detalles Bibliográficos
Autores principales: Dai, Yan-Fen, Zhao, Xing-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427773/
https://www.ncbi.nlm.nih.gov/pubmed/26060814
http://dx.doi.org/10.1155/2015/239654
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author Dai, Yan-Fen
Zhao, Xing-Ming
author_facet Dai, Yan-Fen
Zhao, Xing-Ming
author_sort Dai, Yan-Fen
collection PubMed
description Identifying drug targets plays essential roles in designing new drugs and combating diseases. Unfortunately, our current knowledge about drug targets is far from comprehensive. Screening drug targets in the lab is an expensive and time-consuming procedure. In the past decade, the accumulation of various types of omics data makes it possible to develop computational approaches to predict drug targets. In this paper, we make a survey on the recent progress being made on computational methodologies that have been developed to predict drug targets based on different kinds of omics data and drug property data.
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spelling pubmed-44277732015-06-09 A Survey on the Computational Approaches to Identify Drug Targets in the Postgenomic Era Dai, Yan-Fen Zhao, Xing-Ming Biomed Res Int Review Article Identifying drug targets plays essential roles in designing new drugs and combating diseases. Unfortunately, our current knowledge about drug targets is far from comprehensive. Screening drug targets in the lab is an expensive and time-consuming procedure. In the past decade, the accumulation of various types of omics data makes it possible to develop computational approaches to predict drug targets. In this paper, we make a survey on the recent progress being made on computational methodologies that have been developed to predict drug targets based on different kinds of omics data and drug property data. Hindawi Publishing Corporation 2015 2015-04-28 /pmc/articles/PMC4427773/ /pubmed/26060814 http://dx.doi.org/10.1155/2015/239654 Text en Copyright © 2015 Y.-F. Dai and X.-M. Zhao. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Dai, Yan-Fen
Zhao, Xing-Ming
A Survey on the Computational Approaches to Identify Drug Targets in the Postgenomic Era
title A Survey on the Computational Approaches to Identify Drug Targets in the Postgenomic Era
title_full A Survey on the Computational Approaches to Identify Drug Targets in the Postgenomic Era
title_fullStr A Survey on the Computational Approaches to Identify Drug Targets in the Postgenomic Era
title_full_unstemmed A Survey on the Computational Approaches to Identify Drug Targets in the Postgenomic Era
title_short A Survey on the Computational Approaches to Identify Drug Targets in the Postgenomic Era
title_sort survey on the computational approaches to identify drug targets in the postgenomic era
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427773/
https://www.ncbi.nlm.nih.gov/pubmed/26060814
http://dx.doi.org/10.1155/2015/239654
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