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A Survey on the Computational Approaches to Identify Drug Targets in the Postgenomic Era
Identifying drug targets plays essential roles in designing new drugs and combating diseases. Unfortunately, our current knowledge about drug targets is far from comprehensive. Screening drug targets in the lab is an expensive and time-consuming procedure. In the past decade, the accumulation of var...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427773/ https://www.ncbi.nlm.nih.gov/pubmed/26060814 http://dx.doi.org/10.1155/2015/239654 |
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author | Dai, Yan-Fen Zhao, Xing-Ming |
author_facet | Dai, Yan-Fen Zhao, Xing-Ming |
author_sort | Dai, Yan-Fen |
collection | PubMed |
description | Identifying drug targets plays essential roles in designing new drugs and combating diseases. Unfortunately, our current knowledge about drug targets is far from comprehensive. Screening drug targets in the lab is an expensive and time-consuming procedure. In the past decade, the accumulation of various types of omics data makes it possible to develop computational approaches to predict drug targets. In this paper, we make a survey on the recent progress being made on computational methodologies that have been developed to predict drug targets based on different kinds of omics data and drug property data. |
format | Online Article Text |
id | pubmed-4427773 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-44277732015-06-09 A Survey on the Computational Approaches to Identify Drug Targets in the Postgenomic Era Dai, Yan-Fen Zhao, Xing-Ming Biomed Res Int Review Article Identifying drug targets plays essential roles in designing new drugs and combating diseases. Unfortunately, our current knowledge about drug targets is far from comprehensive. Screening drug targets in the lab is an expensive and time-consuming procedure. In the past decade, the accumulation of various types of omics data makes it possible to develop computational approaches to predict drug targets. In this paper, we make a survey on the recent progress being made on computational methodologies that have been developed to predict drug targets based on different kinds of omics data and drug property data. Hindawi Publishing Corporation 2015 2015-04-28 /pmc/articles/PMC4427773/ /pubmed/26060814 http://dx.doi.org/10.1155/2015/239654 Text en Copyright © 2015 Y.-F. Dai and X.-M. Zhao. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Dai, Yan-Fen Zhao, Xing-Ming A Survey on the Computational Approaches to Identify Drug Targets in the Postgenomic Era |
title | A Survey on the Computational Approaches to Identify Drug Targets in the Postgenomic Era |
title_full | A Survey on the Computational Approaches to Identify Drug Targets in the Postgenomic Era |
title_fullStr | A Survey on the Computational Approaches to Identify Drug Targets in the Postgenomic Era |
title_full_unstemmed | A Survey on the Computational Approaches to Identify Drug Targets in the Postgenomic Era |
title_short | A Survey on the Computational Approaches to Identify Drug Targets in the Postgenomic Era |
title_sort | survey on the computational approaches to identify drug targets in the postgenomic era |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427773/ https://www.ncbi.nlm.nih.gov/pubmed/26060814 http://dx.doi.org/10.1155/2015/239654 |
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