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Hsp72 is targeted to the mitotic spindle by Nek6 to promote K-fiber assembly and mitotic progression
Hsp70 proteins represent a family of chaperones that regulate cellular homeostasis and are required for cancer cell survival. However, their function and regulation in mitosis remain unknown. In this paper, we show that the major inducible cytoplasmic Hsp70 isoform, Hsp72, is required for assembly o...
Autores principales: | O’Regan, Laura, Sampson, Josephina, Richards, Mark W., Knebel, Axel, Roth, Daniel, Hood, Fiona E., Straube, Anne, Royle, Stephen J., Bayliss, Richard, Fry, Andrew M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427782/ https://www.ncbi.nlm.nih.gov/pubmed/25940345 http://dx.doi.org/10.1083/jcb.201409151 |
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