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HBx induced AFP receptor expressed to activate PI3K/AKT signal to promote expression of Src in liver cells and hepatoma cells

BACKGROUND: Hepatitis B virus (HBV)-X protein(HBx) is a transactivator of host several cellular genes including alpha-fetoprotein(AFP) and AFP receptor(AFPR) which contributes to HBV-associated tumor development. The expression of AFP/AFPR are correlated with hepatocellular carcinoma(HCC)-initial ce...

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Detalles Bibliográficos
Autores principales:	Zhu, Mingyue, Guo, Junli, Li, Wei, Xia, Hua, Lu, Yan, Dong, Xu, Chen, Yi, Xie, Xieju, Fu, Shigan, Li, Mengsen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427932/ https://www.ncbi.nlm.nih.gov/pubmed/25943101 http://dx.doi.org/10.1186/s12885-015-1384-9

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