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DisCons: a novel tool to quantify and classify evolutionary conservation of intrinsic protein disorder

BACKGROUND: Analyzing the amino acid sequence of an intrinsically disordered protein (IDP) in an evolutionary context can yield novel insights on the functional role of disordered regions and sequence element(s). However, in the case of many IDPs, the lack of evolutionary conservation of the primary...

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Detalles Bibliográficos
Autores principales: Varadi, Mihaly, Guharoy, Mainak, Zsolyomi, Fruzsina, Tompa, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427981/
https://www.ncbi.nlm.nih.gov/pubmed/25968230
http://dx.doi.org/10.1186/s12859-015-0592-2

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