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DisCons: a novel tool to quantify and classify evolutionary conservation of intrinsic protein disorder
BACKGROUND: Analyzing the amino acid sequence of an intrinsically disordered protein (IDP) in an evolutionary context can yield novel insights on the functional role of disordered regions and sequence element(s). However, in the case of many IDPs, the lack of evolutionary conservation of the primary...
Autores principales: | Varadi, Mihaly, Guharoy, Mainak, Zsolyomi, Fruzsina, Tompa, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427981/ https://www.ncbi.nlm.nih.gov/pubmed/25968230 http://dx.doi.org/10.1186/s12859-015-0592-2 |
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