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Novel monoclonal antibodies against Plasmodium falciparum histidine-rich protein 2: development and application in rapid diagnostic tests of malaria in hyperendemic regions of China and Myanmar

BACKGROUND: Malaria presents a considerable threat to public health. Histidine-rich protein 2 (HRP 2) is the major protein released into human blood upon infection by Plasmodium falciparum. In this study, we aimed to evaluate the immunogenicity of HRP 2 exon II and the efficacy of novel monoclonal a...

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Detalles Bibliográficos
Autores principales: Kang, Keren, Dzakah, Emmanuel E, Li, Wenmei, Xie, Mingquan, Luo, Xiaochun, Liu, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427986/
https://www.ncbi.nlm.nih.gov/pubmed/25962879
http://dx.doi.org/10.1186/s12866-015-0429-1