Computational re-engineering of Amylin sequence with reduced amyloidogenic potential

BACKGROUND: The aggregation of amyloid proteins into fibrils is associated with neurodegenerative diseases such as Alzheimer’s and Type II Diabetes. Different methods have explored ways to impede and inhibit amyloid aggregation. Most attempts in the literature involve applying stress to the environm...

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Detalles Bibliográficos
Autores principales: Smaoui, Mohamed R, Waldispühl, Jérôme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428086/
https://www.ncbi.nlm.nih.gov/pubmed/25903685
http://dx.doi.org/10.1186/s12900-015-0034-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428086/
https://www.ncbi.nlm.nih.gov/pubmed/25903685
http://dx.doi.org/10.1186/s12900-015-0034-4

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