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Dual roles for hepatic lectin receptors in the clearance of chilled platelets

Chilling rapidly (<4 h) clusters Glycoprotein - (GP)Ib receptors on blood platelets, and ß2-integrins of hepatic macrophages bind ßGlcNAc residues in the clusters leading to rapid clearance of acutely chilled platelets following transfusion. Although capping the ßGlcNAc moieties by galactosylatio...

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Detalles Bibliográficos
Autores principales: Rumjantseva, Viktoria, Grewal, Prabhjit K., Wandall, Hans H., Josefsson, Emma C., Sørensen, Anne Louise, Larson, Göran, Marth, Jamey D., Hartwig, John H., Hoffmeister, Karin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428152/
https://www.ncbi.nlm.nih.gov/pubmed/19783995
http://dx.doi.org/10.1038/nm.2030