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Dual roles for hepatic lectin receptors in the clearance of chilled platelets
Chilling rapidly (<4 h) clusters Glycoprotein - (GP)Ib receptors on blood platelets, and ß2-integrins of hepatic macrophages bind ßGlcNAc residues in the clusters leading to rapid clearance of acutely chilled platelets following transfusion. Although capping the ßGlcNAc moieties by galactosylatio...
Autores principales: | Rumjantseva, Viktoria, Grewal, Prabhjit K., Wandall, Hans H., Josefsson, Emma C., Sørensen, Anne Louise, Larson, Göran, Marth, Jamey D., Hartwig, John H., Hoffmeister, Karin M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428152/ https://www.ncbi.nlm.nih.gov/pubmed/19783995 http://dx.doi.org/10.1038/nm.2030 |
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