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Calcium-responsive transactivator (CREST) protein shares a set of structural and functional traits with other proteins associated with amyotrophic lateral sclerosis

BACKGROUND: Mutations in calcium-responsive transactivator (CREST) encoding gene have been recently linked to ALS. Similar to several proteins implicated in ALS, CREST contains a prion-like domain and was reported to be a component of paraspeckles. RESULTS: We demonstrate that CREST is prone to aggr...

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Detalles Bibliográficos
Autores principales:	Kukharsky, Michail S, Quintiero, Annamaria, Matsumoto, Taisei, Matsukawa, Koji, An, Haiyan, Hashimoto, Tadafumi, Iwatsubo, Takeshi, Buchman, Vladimir L, Shelkovnikova, Tatyana A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428507/ https://www.ncbi.nlm.nih.gov/pubmed/25888396 http://dx.doi.org/10.1186/s13024-015-0014-y

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