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Sleep Physiology Alterations Precede Plethoric Phenotypic Changes in R6/1 Huntington’s Disease Mice

In hereditary neurodegenerative Huntington’s disease (HD), there exists a growing consideration that sleep and circadian dysregulations may be important symptoms. It is not known, however, whether sleep abnormalities contribute to other behavioral deficits in HD patients and mouse models. To determi...

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Detalles Bibliográficos
Autores principales: Lebreton, Fanny, Cayzac, Sebastien, Pietropaolo, Susanna, Jeantet, Yannick, Cho, Yoon H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428700/
https://www.ncbi.nlm.nih.gov/pubmed/25966356
http://dx.doi.org/10.1371/journal.pone.0126972