Cargando…

Protective Effects of Silibinin and Its Possible Mechanism of Action in Mice Exposed to Chronic Unpredictable Mild Stress

Silibinin, a natural flavonoid antioxidant isolated from extracts of the milk thistle herb, has recently been identified as having anti-hepatotoxic and anticancer properties. In this paper, we investigated the effects of silibinin on behavior and neuroplasticity in mice subjected to chronic unpredic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yan, Wen-Jing, Tan, Ying-Chun, Xu, Ji-Cheng, Tang, Xian-Ping, Zhang, Chong, Zhang, Peng-Bo, Ren, Ze-Qiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Society of Applied Pharmacology 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428717/ https://www.ncbi.nlm.nih.gov/pubmed/25995823 http://dx.doi.org/10.4062/biomolther.2014.138

Ejemplares similares

Acupuncture Activates ERK-CREB Pathway in Rats Exposed to Chronic Unpredictable Mild Stress
por: Lu, Jun, et al.
Publicado: (2013)

Baicalin improves the energy levels in the prefrontal cortex of mice exposed to chronic unpredictable mild stress
por: Lu, Shuaifei, et al.
Publicado: (2022)

Chronic clomipramine treatment increases hippocampal volume in rats exposed to chronic unpredictable mild stress
por: Zhang, Shanshan, et al.
Publicado: (2022)

The Impacts of Swimming Exercise on Hippocampal Expression of Neurotrophic Factors in Rats Exposed to Chronic Unpredictable Mild Stress
por: Jiang, Pei, et al.
Publicado: (2014)

Effects of the Ethanol Extract of Dipterocarpus alatus Leaf on the Unpredictable Chronic Mild Stress-Induced Depression in ICR Mice and Its Possible Mechanism of Action
por: Daodee, Supawadee, et al.
Publicado: (2019)

Ocimum basilicum (Basil) Modulates Apoptosis and Neurogenesis in Olfactory Pulp of Mice Exposed to Chronic Unpredictable Mild Stress
por: Ayuob, Nasra N., et al.
Publicado: (2020)

Re-evaluation of the interrelationships among the behavioral tests in rats exposed to chronic unpredictable mild stress
por: Hu, Congli, et al.
Publicado: (2017)

Effect of Vitamin D3 on Depressive Behaviors of Rats Exposed to Chronic Unpredictable Mild Stress
por: Al-Ramadhan, Fatimah R., et al.
Publicado: (2023)

Antidepressant Effects of Rhodomyrtone in Mice with Chronic Unpredictable Mild Stress-Induced Depression
por: Chai, Huihui, et al.
Publicado: (2018)

Corrigendum: Ocimum basilicum (Basil) Modulates Apoptosis and Neurogenesis in Olfactory Pulp of Mice Exposed to Chronic Unpredictable Mild Stress
por: Ayuob, Nasra N., et al.
Publicado: (2021)

Hydrogen Sulfide Protects against Chronic Unpredictable Mild Stress-Induced Oxidative Stress in Hippocampus by Upregulation of BDNF-TrkB Pathway
por: Hu, Min, et al.
Publicado: (2016)

Evaluation of behavioural and antioxidant activity of Cytisus scoparius Link in rats exposed to chronic unpredictable mild stress
por: Nirmal, Jayabalan, et al.
Publicado: (2008)

Altered gut metabolome contributes to depression-like behaviors in rats exposed to chronic unpredictable mild stress
por: Jianguo, Li, et al.
Publicado: (2019)

Chronic Unpredictable Mild Stress Model of Depression: Possible Sources of Poor Reproducibility and Latent Variables
por: Markov, Dmitrii D., et al.
Publicado: (2022)

Antidepressants fluoxetine and amitriptyline induce alterations in intestinal microbiota and gut microbiome function in rats exposed to chronic unpredictable mild stress
por: Zhang, Weijie, et al.
Publicado: (2021)

Correction: Altered gut metabolome contributes to depression-like behaviors in rats exposed to chronic unpredictable mild stress
por: Jianguo, Li, et al.
Publicado: (2019)

Regulation of Tau Protein on the Antidepressant Effects of Ketamine in the Chronic Unpredictable Mild Stress Model
por: Wen, Gehua, et al.
Publicado: (2019)

Wound Healing Activity of Silibinin in Mice
por: Samanta, Rojalini, et al.
Publicado: (2016)

The Influence of Topinambur and Inulin Preventive Supplementation on Microbiota, Anxious Behavior, Cognitive Functions and Neurogenesis in Mice Exposed to the Chronic Unpredictable Mild Stress
por: Szala-Rycaj, Joanna, et al.
Publicado: (2023)

Emodin Prevented Depression in Chronic Unpredicted Mild Stress-Exposed Rats by Targeting miR-139-5p/5-Lipoxygenase
por: Zhang, Teng, et al.
Publicado: (2021)

Ingestion of Gouda Cheese Ameliorates the Chronic Unpredictable Mild Stress in Mice
por: Yun, Bohyun, et al.
Publicado: (2020)

Antidepressant-Like Effects of Cordycepin in a Mice Model of Chronic Unpredictable Mild Stress
por: Tianzhu, Zhang, et al.
Publicado: (2014)

Perturbation of mitiglinide metabolism by chronic unpredicted mild stress in rats
por: Zeng, Yingtong, et al.
Publicado: (2014)

Systematic impacts of chronic unpredictable mild stress on metabolomics in rats
por: Geng, Chunmei, et al.
Publicado: (2020)

Antidepressant‐like effect of flaxseed in rats exposed to chronic unpredictable stress
por: Han, Yan, et al.
Publicado: (2020)

Unveiling behavioral and molecular neuroadaptations related to the antidepressant action of cannabidiol in the unpredictable chronic mild stress model
por: García-Gutiérrez, María Salud, et al.
Publicado: (2023)

Apocynum venetum Leaf Extract Exerts Antidepressant-Like Effects and Inhibits Hippocampal and Cortical Apoptosis of Rats Exposed to Chronic Unpredictable Mild Stress
por: Wu, Ting, et al.
Publicado: (2018)

The Antidepressant Agomelatine Improves Memory Deterioration and Upregulates CREB and BDNF Gene Expression Levels in Unpredictable Chronic Mild Stress (UCMS)-Exposed Mice
por: Gumuslu, Esen, et al.
Publicado: (2014)

Fish oil supplementation alleviates depressant-like behaviors and modulates lipid profiles in rats exposed to chronic unpredictable mild stress
por: Tang, Mimi, et al.
Publicado: (2015)

Short Term Intrarectal Administration of Sodium Propionate Induces Antidepressant-Like Effects in Rats Exposed to Chronic Unpredictable Mild Stress
por: Li, Jianguo, et al.
Publicado: (2018)

Behavioral and Biochemical Interaction Between Nicotine and Chronic Unpredictable Mild Stress in Mice
por: Biala, G., et al.
Publicado: (2016)

Photobiomodulation Therapy Ameliorates Glutamatergic Dysfunction in Mice with Chronic Unpredictable Mild Stress-Induced Depression
por: Zhang, Di, et al.
Publicado: (2021)

Silibinin: an old drug for hematological disorders
por: Zou, Hai, et al.
Publicado: (2017)

The Effect of Silibinin on Protein Expression Profile in White Adipose Tissue of Obese Mice
por: Wang, Fei, et al.
Publicado: (2020)

Effects of regulating gut microbiota on the serotonin metabolism in the chronic unpredictable mild stress rat model
por: Li, Huawei, et al.
Publicado: (2019)

Effect of chronic unpredicted mild stress-induced depression on clopidogrel pharmacokinetics in rats
por: Jiang, Xueyao, et al.
Publicado: (2022)

Gut microbiota decreased inflammation induced by chronic unpredictable mild stress through affecting NLRP3 inflammasome
por: Huang, Li, et al.
Publicado: (2023)

Suppressive Effects of Isofraxidin on Depressive-like Behaviors Induced by Chronic Unpredictable Mild Stress in Mice
por: Wu, Xiaoli, et al.
Publicado: (2022)

Combined probiotics attenuate chronic unpredictable mild stress-induced depressive-like and anxiety-like behaviors in rats
por: Huang, Li, et al.
Publicado: (2022)

Dermointegration in the exposed titanium cranioplasty: a possible protective phenomenon
por: Zhang, Steven Liben, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_uh9vda45cv5atiik87mqa8654r