Recommendations for Accurate Resolution of Gene and Isoform Allele-Specific Expression in RNA-Seq Data

Genetic variation modulates gene expression transcriptionally or post-transcriptionally, and can profoundly alter an individual’s phenotype. Measuring allelic differential expression at heterozygous loci within an individual, a phenomenon called allele-specific expression (ASE), can assist in identi...

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Detalles Bibliográficos
Autores principales: Wood, David L. A., Nones, Katia, Steptoe, Anita, Christ, Angelika, Harliwong, Ivon, Newell, Felicity, Bruxner, Timothy J. C., Miller, David, Cloonan, Nicole, Grimmond, Sean M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428808/
https://www.ncbi.nlm.nih.gov/pubmed/25965996
http://dx.doi.org/10.1371/journal.pone.0126911

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