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RNase HI Is Essential for Survival of Mycobacterium smegmatis

RNases H are involved in the removal of RNA from RNA/DNA hybrids. Type I RNases H are thought to recognize and cleave the RNA/DNA duplex when at least four ribonucleotides are present. Here we investigated the importance of RNase H type I encoding genes for model organism Mycobacterium smegmatis. By...

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Detalles Bibliográficos
Autores principales: Minias, Alina E., Brzostek, Anna M., Korycka- Machala, Malgorzata, Dziadek, Bozena, Minias, Piotr, Rajagopalan, Malini, Madiraju, Murty, Dziadek, Jaroslaw
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429107/
https://www.ncbi.nlm.nih.gov/pubmed/25965344
http://dx.doi.org/10.1371/journal.pone.0126260