Cargando…

A Temperature-Monitoring Vaginal Ring for Measuring Adherence

BACKGROUND: Product adherence is a pivotal issue in the development of effective vaginal microbicides to reduce sexual transmission of HIV. To date, the six Phase III studies of vaginal gel products have relied primarily on self-reporting of adherence. Accurate and reliable methods for monitoring us...

Descripción completa

Detalles Bibliográficos
Autores principales:	Boyd, Peter, Desjardins, Delphine, Kumar, Sandeep, Fetherston, Susan M., Le-Grand, Roger, Dereuddre-Bosquet, Nathalie, Helgadóttir, Berglind, Bjarnason, Ásgeir, Narasimhan, Manjula, Malcolm, R. Karl
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429109/ https://www.ncbi.nlm.nih.gov/pubmed/25965956 http://dx.doi.org/10.1371/journal.pone.0125682

Ejemplares similares

Vaginal rings for delivery of HIV microbicides
por: Malcolm, R Karl, et al.
Publicado: (2012)

Mucosal application of the broadly neutralizing antibody 10-1074 protects macaques from cell-associated SHIV vaginal exposure
por: Suphaphiphat, Karunasinee, et al.
Publicado: (2023)

Pharmacological Validation of Long-Term Treatment with Antiretroviral Drugs in a Model of SIV-Infected Non-Human Primates
por: Gelé, Thibaut, et al.
Publicado: (2022)

Broadly neutralizing antibodies potently inhibit cell-to-cell transmission of semen leukocyte-derived SHIV162P3
por: Suphaphiphat, Karunasinee, et al.
Publicado: (2020)

CD4-mimetic sulfopeptide conjugates display sub-nanomolar anti-HIV-1 activity and protect macaques against a SHIV162P3 vaginal challenge
por: Ariën, Kevin K., et al.
Publicado: (2016)

Identification of CX3CR1(+) mononuclear phagocyte subsets involved in HIV-1 and SIV colorectal transmission
por: Cavarelli, Mariangela, et al.
Publicado: (2022)

The Vaginal Microbiota, Bacterial Biofilms and Polymeric Drug-Releasing Vaginal Rings
por: Carson, Louise, et al.
Publicado: (2021)

Cynomolgus macaque IL37 polymorphism and control of SIV infection
por: Shiina, Takashi, et al.
Publicado: (2019)

Towards a vaccine against AIDS
por: Vieillard, Vincent, et al.
Publicado: (2010)

Non-neutralizing IgG anti-PID antibodies decreased viral load following high dose vaginal challenge of non-human primates
por: Moog, C, et al.
Publicado: (2012)

Use of simulated vaginal and menstrual fluids to model in vivo discolouration of silicone elastomer vaginal rings
por: McCoy, Clare F., et al.
Publicado: (2021)

MiniCD4 Microbicide Prevents HIV Infection of Human Mucosal Explants and Vaginal Transmission of SHIV(162P3) in Cynomolgus Macaques
por: Dereuddre-Bosquet, Nathalie, et al.
Publicado: (2012)

Superior Efficacy of a Human Immunodeficiency Virus Vaccine Combined with Antiretroviral Prevention in Simian-Human Immunodeficiency Virus-Challenged Nonhuman Primates
por: Le Grand, Roger, et al.
Publicado: (2016)

Semen CD4(+) T Cells and Macrophages Are Productively Infected at All Stages of SIV infection in Macaques
por: Bernard-Stoecklin, Sibylle, et al.
Publicado: (2013)

Effect of a short-term HAART on SIV load in macaque tissues is dependent on time of initiation and antiviral diffusion
por: Bourry, Olivier, et al.
Publicado: (2010)

Color, Scent and Size: Exploring Women's Preferences Around Design Characteristics of Drug-Releasing Vaginal Rings
por: Zhao, Xinyu, et al.
Publicado: (2022)

Overcoming immunogenicity issues of HIV p24 antigen by the use of innovative nanostructured lipid carriers as delivery systems: evidences in mice and non-human primates
por: Bayon, Emilie, et al.
Publicado: (2018)

Leukocytospermia induces intraepithelial recruitment of dendritic cells and increases SIV replication in colorectal tissue explants
por: Cavarelli, Mariangela, et al.
Publicado: (2021)

Biomarkers and biometric measures of adherence to use of ARV-based vaginal rings
por: Stalter, Randy M, et al.
Publicado: (2016)

Vaginal rings with exposed cores for sustained delivery of the HIV CCR5 inhibitor 5P12-RANTES
por: McBride, John W., et al.
Publicado: (2019)

Plasmacytoid Dendritic Cell Dynamics Tune Interferon-Alfa Production in SIV-Infected Cynomolgus Macaques
por: Bruel, Timothée, et al.
Publicado: (2014)

Molecular and Cellular Dynamics in the Skin, the Lymph Nodes, and the Blood of the Immune Response to Intradermal Injection of Modified Vaccinia Ankara Vaccine
por: Rosenbaum, Pierre, et al.
Publicado: (2018)

NK-B cell cross talk induces CXCR5 expression on natural killer cells
por: Rascle, Philippe, et al.
Publicado: (2021)

Refining the in vitro release test method for a dapivirine-releasing vaginal ring to match in vivo performance
por: Murphy, Diarmaid J., et al.
Publicado: (2021)

DC Subsets Regulate Humoral Immune Responses by Supporting the Differentiation of Distinct Tfh Cells
por: Bouteau, Aurélie, et al.
Publicado: (2019)

Innate and Adaptive Anti-SIV Responses in Macaque Semen: Implications for Infectivity and Risk of Transmission
por: Suphaphiphat, Karunasinee, et al.
Publicado: (2020)

Silicone elastomer formulations for improved performance of a multipurpose vaginal ring releasing dapivirine and levonorgestrel
por: Dallal Bashi, Yahya H., et al.
Publicado: (2021)

An interdisciplinary framework for measuring and supporting adherence in HIV prevention trials of ARV-based vaginal rings
por: MacQueen, Kathleen M, et al.
Publicado: (2014)

Post-use assay of vaginal rings (VRs) as a potential measure of clinical trial adherence
por: Spence, Patrick, et al.
Publicado: (2016)

Whole genome sequencing in the search for genes associated with the control of SIV infection in the Mauritian macaque model
por: de Manuel, Marc, et al.
Publicado: (2018)

Detection of SARS-CoV-2 in subcutaneous fat but not visceral fat, and the disruption of fat lymphocyte homeostasis in both fat tissues in the macaque
por: Olivo, Anaëlle, et al.
Publicado: (2022)

Multi-component prime-boost Chlamydia trachomatis vaccination regimes induce antibody and T cell responses and accelerate clearance of infection in a non-human primate model
por: Lorenzen, Emma, et al.
Publicado: (2022)

Delivering HIV Gagp24 to DCIR Induces Strong Antibody Responses In Vivo
por: Flamar, Anne-Laure, et al.
Publicado: (2015)

Prime and Boost Vaccination Elicit a Distinct Innate Myeloid Cell Immune Response
por: Palgen, Jean-Louis, et al.
Publicado: (2018)

Innate and secondary humoral responses are improved by increasing the time between MVA vaccine immunizations
por: Palgen, Jean-Louis, et al.
Publicado: (2020)

Effectiveness of CHIKV vaccine VLA1553 demonstrated by passive transfer of human sera
por: Roques, Pierre, et al.
Publicado: (2022)

Review of the combined contraceptive vaginal ring, NuvaRing(®)
por: Roumen, Frans JME
Publicado: (2008)

Acceptability of the Dapivirine Vaginal Ring for HIV-1 Prevention and Association with Adherence in a Phase III Trial
por: Mayo, Ashley J., et al.
Publicado: (2021)

Laser capture microdissection enables transcriptomic analysis of dividing and quiescent liver stages of Plasmodium relapsing species
por: Cubi, Roger, et al.
Publicado: (2017)

Chloroquine Potentiates Primaquine Activity against Active and Latent Hepatic Plasmodia Ex Vivo: Potentials and Pitfalls
por: Dembélé, Laurent, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_4uk9197ecop6tsbsobhrv50qu9