Cargando…

Expression of the Carboxy-Terminal Portion of MUC16/CA125 Induces Transformation and Tumor Invasion

The CA125 antigen is found in the serum of many patients with serous ovarian cancer and has been widely used as a disease marker. CA125 has been shown to be an independent factor for clinical outcome in this disease. In The Cancer Genome Atlas ovarian cancer project, MUC16 expression levels are freq...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rao, Thapi D., Tian, Huasong, Ma, Xun, Yan, Xiujun, Thapi, Sahityasri, Schultz, Nikolaus, Rosales, Nestor, Monette, Sebastien, Wang, Amy, Hyman, David M., Levine, Douglas A., Solit, David, Spriggs, David R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429113/ https://www.ncbi.nlm.nih.gov/pubmed/25965947 http://dx.doi.org/10.1371/journal.pone.0126633

Ejemplares similares

Targeting galectin-3 with a high-affinity antibody for inhibition of high-grade serous ovarian cancer and other MUC16/CA-125-expressing malignancies
por: Stasenko, Marina, et al.
Publicado: (2021)

SUN-417 Recovery Of Central Adrenal Insufficiency In A Patient With Hypophysitis Secondary To Immune Checkpoint Inhibitors Therapy
por: Thapi, Sahityasri, et al.
Publicado: (2019)

Recovery from secondary adrenal insufficiency in a patient with immune checkpoint inhibitor therapy induced hypophysitis
por: Thapi, Sahityasri, et al.
Publicado: (2019)

Barriers to Follow Up Care in the South Asian Immigrant Population at High Risk of Acute Coronary Syndrome at Elmhurst Hospital Center
por: Thapi, Sahityasri, et al.
Publicado: (2022)

SUN-626 Survival of Patients with Gastroenteropancreatic Neuroendocrine Tumors and Diabetes Mellitus in a Seer-Medicare Cohort
por: Thapi, Sahityasri, et al.
Publicado: (2020)

Bispecific T-Cell Engaging Antibodies Against MUC16 Demonstrate Efficacy Against Ovarian Cancer in Monotherapy and in Combination With PD-1 and VEGF Inhibition
por: Yeku, Oladapo O., et al.
Publicado: (2021)

Association of Reduced Hospitalizations and Mortality Rates Among COVID-19-Vaccinated Patients With Heart Failure
por: JOHNSON, KIPP W., et al.
Publicado: (2022)

Import of the carboxy-terminal portion of acyl-CoA oxidase into peroxisomes of Candida tropicalis
Publicado: (1987)

Effect of treatment center volume on outcomes in gastroenteropancreatic neuroendocrine tumor patients
por: Baeg, Kiwoon, et al.
Publicado: (2021)

Autophagic Removal of Farnesylated Carboxy-Terminal Lamin Peptides
por: Lu, Xiang, et al.
Publicado: (2018)

Activity of the Carboxy-Terminal Peptide Region of the Teneurins and Its Role in Neuronal Function and Behavior in Mammals
por: Hogg, David W., et al.
Publicado: (2019)

CA125/MUC16 Is Dispensable for Mouse Development and Reproduction
por: Cheon, Dong-Joo, et al.
Publicado: (2009)

Carboxy-terminal Determinants of Conductance in Inward-rectifier K Channels
por: Zhang, Yu-Yang, et al.
Publicado: (2004)

The Carboxy-Terminal Modulator Protein (CTMP) Regulates Mitochondrial Dynamics
por: Parcellier, Arnaud, et al.
Publicado: (2009)

On the computational ability of the RNA polymerase II carboxy terminal domain
por: Karagiannis, Jim
Publicado: (2014)

Development and characterization of carboxy-terminus specific monoclonal antibodies for understanding MUC16 cleavage in human ovarian cancer
por: Aithal, Abhijit, et al.
Publicado: (2018)

Polymorphisms of MUC16 (CA125) and MUC1 (CA15.3) in Relation to Ovarian Cancer Risk and Survival
por: Williams, Kristina A., et al.
Publicado: (2014)

Driving forces behind phase separation of the carboxy-terminal domain of RNA polymerase II
por: Flores-Solis, David, et al.
Publicado: (2023)

The Circadian Rhythm of Copeptin, the C-Terminal Portion of Arginine Vasopressin
por: Beglinger, Svetlana, et al.
Publicado: (2017)

Arrest of Development of Large Intestine and Terminal Portion of Small Intestine
Publicado: (1913)

Decoding the informational properties of the RNA polymerase II Carboxy Terminal Domain
por: Karagiannis, Jim
Publicado: (2012)

Regulation of microtubule dynamic instability by the carboxy-terminal tail of β-tubulin
por: Fees, Colby P, et al.
Publicado: (2018)

Conflicting Views on the Molecular Structure of the Cancer Antigen CA125/MUC16
por: Bouanene, Houda, et al.
Publicado: (2010)

Identification of conserved gene structures and carboxy-terminal motifs in the Myb gene family of Arabidopsis and Oryza sativa L. ssp. indica
por: Jiang, Cizhong, et al.
Publicado: (2004)

Case of Intussusception, Terminating in Sloughing and Discharge of the Intussuscepted Portion of Intestine; and Recovery
por: Brydon, James
Publicado: (1866)

Molecular dissection of radixin: distinct and interdependent functions of the amino- and carboxy-terminal domains
Publicado: (1995)

The carboxy terminal coiled-coil modulates Orai1 internalization during meiosis
por: Hodeify, Rawad, et al.
Publicado: (2021)

Exploring the Ability of LARS2 Carboxy-Terminal Domain in Rescuing the MELAS Phenotype
por: Capriglia, Francesco, et al.
Publicado: (2021)

HN125: A Novel Immunoadhesin Targeting MUC16 with Potential for Cancer Therapy
por: Xiang, Xinran, et al.
Publicado: (2011)

MUC16 (CA125): tumor biomarker to cancer therapy, a work in progress
por: Felder, Mildred, et al.
Publicado: (2014)

Knockdown of MUC16 (CA125) Enhances the Migration and Invasion of Hepatocellular Carcinoma Cells
por: Huang, Yao, et al.
Publicado: (2021)

Individual recombinant repeats of MUC16 display variable binding to CA125 antibodies
por: Wang, Chien-Wei, et al.
Publicado: (2023)

Brr2p carboxy-terminal Sec63 domain modulates Prp16 splicing RNA helicase
por: Cordin, Olivier, et al.
Publicado: (2014)

Potentiation of Neuronal Nicotinic Receptors by 17β-Estradiol: Roles of the Carboxy-Terminal and the Amino-Terminal Extracellular Domains
por: Jin, Xiaochun, et al.
Publicado: (2015)

PORCN Negatively Regulates AMPAR Function Independently of Subunit Composition and the Amino-Terminal and Carboxy-Terminal Domains of AMPARs
por: Wei, Mengping, et al.
Publicado: (2020)

The C-Terminal Portion of the Nucleocapsid Protein Demonstrates SARS-CoV Antigenicity
por: Liu, Guozhen, et al.
Publicado: (2003)

Case of Fracture of the Occipital Bone with the Loss of a Portion of the Cerebellum, Terminating Favorably
por: Evans, J.
Publicado: (1804)

A case control study investigating factors associated with high infant death in Saiha district of Mizoram, India bordering Myanmar
por: Deb, Alok K., et al.
Publicado: (2017)

Modification of the carboxy-terminal flanking region of a universal influenza epitope alters CD4(+) T-cell repertoire selection
por: Cole, David K., et al.
Publicado: (2012)

The carboxy-terminal domain of Gs alpha is necessary for anchorage of the activated form in the plasma membrane
Publicado: (1990)

Cannot write session to /tmp/vufind_sessions/sess_3od5lp8bpffu2quokhetae1nkj