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Effect of Noise in Intelligent Cellular Decision Making

Similar to intelligent multicellular neural networks controlling human brains, even single cells, surprisingly, are able to make intelligent decisions to classify several external stimuli or to associate them. This happens because of the fact that gene regulatory networks can perform as perceptrons,...

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Detalles Bibliográficos
Autores principales: Bates, Russell, Blyuss, Oleg, Alsaedi, Ahmed, Zaikin, Alexey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429125/
https://www.ncbi.nlm.nih.gov/pubmed/25965584
http://dx.doi.org/10.1371/journal.pone.0125079
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author Bates, Russell
Blyuss, Oleg
Alsaedi, Ahmed
Zaikin, Alexey
author_facet Bates, Russell
Blyuss, Oleg
Alsaedi, Ahmed
Zaikin, Alexey
author_sort Bates, Russell
collection PubMed
description Similar to intelligent multicellular neural networks controlling human brains, even single cells, surprisingly, are able to make intelligent decisions to classify several external stimuli or to associate them. This happens because of the fact that gene regulatory networks can perform as perceptrons, simple intelligent schemes known from studies on Artificial Intelligence. We study the role of genetic noise in intelligent decision making at the genetic level and show that noise can play a constructive role helping cells to make a proper decision. We show this using the example of a simple genetic classifier able to classify two external stimuli.
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spelling pubmed-44291252015-05-21 Effect of Noise in Intelligent Cellular Decision Making Bates, Russell Blyuss, Oleg Alsaedi, Ahmed Zaikin, Alexey PLoS One Research Article Similar to intelligent multicellular neural networks controlling human brains, even single cells, surprisingly, are able to make intelligent decisions to classify several external stimuli or to associate them. This happens because of the fact that gene regulatory networks can perform as perceptrons, simple intelligent schemes known from studies on Artificial Intelligence. We study the role of genetic noise in intelligent decision making at the genetic level and show that noise can play a constructive role helping cells to make a proper decision. We show this using the example of a simple genetic classifier able to classify two external stimuli. Public Library of Science 2015-05-12 /pmc/articles/PMC4429125/ /pubmed/25965584 http://dx.doi.org/10.1371/journal.pone.0125079 Text en © 2015 Bates et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Bates, Russell
Blyuss, Oleg
Alsaedi, Ahmed
Zaikin, Alexey
Effect of Noise in Intelligent Cellular Decision Making
title Effect of Noise in Intelligent Cellular Decision Making
title_full Effect of Noise in Intelligent Cellular Decision Making
title_fullStr Effect of Noise in Intelligent Cellular Decision Making
title_full_unstemmed Effect of Noise in Intelligent Cellular Decision Making
title_short Effect of Noise in Intelligent Cellular Decision Making
title_sort effect of noise in intelligent cellular decision making
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429125/
https://www.ncbi.nlm.nih.gov/pubmed/25965584
http://dx.doi.org/10.1371/journal.pone.0125079
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