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Prolonged Treatment with Inhaled Corticosteroids does not Normalize High Activity of Matrix Metalloproteinase-9 in Exhaled Breath Condensates of Children with Asthma

The airway remodeling in asthma is associated with increased amount of matrix metalloproteinase (MMP)-9. High levels of MMP-9 were found in mucosal biopsies, sputum and in exhaled breath condensates (EBC) of asthma patients. However, there are no data concerning real in vivo activity. Inhaled cortic...

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Detalles Bibliográficos
Autores principales: Grzela, Katarzyna, Zagorska, Wioletta, Krejner, Alicja, Litwiniuk, Malgorzata, Zawadzka-Krajewska, Anna, Banaszkiewicz, Aleksandra, Kulus, Marek, Grzela, Tomasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Basel 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429133/
https://www.ncbi.nlm.nih.gov/pubmed/25650123
http://dx.doi.org/10.1007/s00005-015-0328-z

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