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Innervation zones of fasciculating motor units: observations by a linear electrode array
This study examines the innervation zone (IZ) in the biceps brachii muscle in healthy subjects and those with amyotrophic lateral sclerosis (ALS) using a 20-channel linear electromyogram (EMG) electrode array. Raster plots of individual waveform potentials were studied to estimate the motor unit IZ....
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429247/ https://www.ncbi.nlm.nih.gov/pubmed/26029076 http://dx.doi.org/10.3389/fnhum.2015.00239 |
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author | Jahanmiri-Nezhad, Faezeh Barkhaus, Paul E. Rymer, William Z. Zhou, Ping |
author_facet | Jahanmiri-Nezhad, Faezeh Barkhaus, Paul E. Rymer, William Z. Zhou, Ping |
author_sort | Jahanmiri-Nezhad, Faezeh |
collection | PubMed |
description | This study examines the innervation zone (IZ) in the biceps brachii muscle in healthy subjects and those with amyotrophic lateral sclerosis (ALS) using a 20-channel linear electromyogram (EMG) electrode array. Raster plots of individual waveform potentials were studied to estimate the motor unit IZ. While this work mainly focused on fasciculation potentials (FPs), a limited number of motor unit potentials (MUPs) from voluntary activity of 12 healthy and seven ALS subjects were also examined. Abnormal propagation of MUPs and scattered IZs were observed in fasciculating units, compared with voluntarily activated MUPs in healthy and ALS subjects. These findings can be related to muscle fiber reinnervation following motor neuron degeneration in ALS and the different origin sites of FPs compared with voluntary MUPs. |
format | Online Article Text |
id | pubmed-4429247 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-44292472015-05-29 Innervation zones of fasciculating motor units: observations by a linear electrode array Jahanmiri-Nezhad, Faezeh Barkhaus, Paul E. Rymer, William Z. Zhou, Ping Front Hum Neurosci Neuroscience This study examines the innervation zone (IZ) in the biceps brachii muscle in healthy subjects and those with amyotrophic lateral sclerosis (ALS) using a 20-channel linear electromyogram (EMG) electrode array. Raster plots of individual waveform potentials were studied to estimate the motor unit IZ. While this work mainly focused on fasciculation potentials (FPs), a limited number of motor unit potentials (MUPs) from voluntary activity of 12 healthy and seven ALS subjects were also examined. Abnormal propagation of MUPs and scattered IZs were observed in fasciculating units, compared with voluntarily activated MUPs in healthy and ALS subjects. These findings can be related to muscle fiber reinnervation following motor neuron degeneration in ALS and the different origin sites of FPs compared with voluntary MUPs. Frontiers Media S.A. 2015-05-12 /pmc/articles/PMC4429247/ /pubmed/26029076 http://dx.doi.org/10.3389/fnhum.2015.00239 Text en Copyright © 2015 Jahanmiri-Nezhad, Barkhaus, Rymer and Zhou. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Neuroscience Jahanmiri-Nezhad, Faezeh Barkhaus, Paul E. Rymer, William Z. Zhou, Ping Innervation zones of fasciculating motor units: observations by a linear electrode array |
title | Innervation zones of fasciculating motor units: observations by a linear electrode array |
title_full | Innervation zones of fasciculating motor units: observations by a linear electrode array |
title_fullStr | Innervation zones of fasciculating motor units: observations by a linear electrode array |
title_full_unstemmed | Innervation zones of fasciculating motor units: observations by a linear electrode array |
title_short | Innervation zones of fasciculating motor units: observations by a linear electrode array |
title_sort | innervation zones of fasciculating motor units: observations by a linear electrode array |
topic | Neuroscience |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429247/ https://www.ncbi.nlm.nih.gov/pubmed/26029076 http://dx.doi.org/10.3389/fnhum.2015.00239 |
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