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Heat fixation inactivates viral and bacterial pathogens and is compatible with downstream MALDI mass spectrometry tissue imaging
BACKGROUND: Tissue samples should be fixed and permanently stabilized as soon as possible ex-vivo to avoid variations in proteomic content. Tissues collected from studies involving infectious microorganisms, must face the additional challenge of pathogen inactivation before downstream proteomic anal...
Autores principales: | Cazares, Lisa H, Van Tongeren, Sean A, Costantino, Julie, Kenny, Tara, Garza, Nicole L, Donnelly, Ginger, Lane, Douglas, Panchal, Rekha G, Bavari, Sina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429342/ https://www.ncbi.nlm.nih.gov/pubmed/25966989 http://dx.doi.org/10.1186/s12866-015-0431-7 |
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