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De novo identification of differentially methylated regions in the human genome

BACKGROUND: The identification and characterisation of differentially methylated regions (DMRs) between phenotypes in the human genome is of prime interest in epigenetics. We present a novel method, DMRcate, that fits replicated methylation measurements from the Illumina HM450K BeadChip (or 450K arr...

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Detalles Bibliográficos
Autores principales:	Peters, Timothy J, Buckley, Michael J, Statham, Aaron L, Pidsley, Ruth, Samaras, Katherine, V Lord, Reginald, Clark, Susan J, Molloy, Peter L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Methodology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429355/ https://www.ncbi.nlm.nih.gov/pubmed/25972926 http://dx.doi.org/10.1186/1756-8935-8-6

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