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Patterns of thyroid hormone levels in pediatric medullary thyroid carcinoma patients on vandetanib therapy

BACKGROUND: Tyrosine kinase inhibitors (TKIs) have been associated with elevated TSH as a drug class effect. Prior studies of vandetanib in adults with medullary thyroid carcinoma (MTC) described an increase in levothyroxine (LT) requirement. We studied TSH, free T4, and LT dosing in children and ad...

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Detalles Bibliográficos
Autores principales:	Lodish, Maya, Gkourogianni, Alexandra, Bornstein, Ethan, Sinaii, Ninet, Fox, Elizabeth, Chuk, Meredith, Marcus, Leigh, Akshintala, Srivandana, Balis, Frank, Widemann, Brigitte, Stratakis, Constantine A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429462/ https://www.ncbi.nlm.nih.gov/pubmed/25972901 http://dx.doi.org/10.1186/1687-9856-2015-3

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