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Effect of targeted estrogen delivery using glucagon-like peptide-1 on insulin secretion, insulin sensitivity and glucose homeostasis

The female estrogen 17β-estradiol (E2) enhances pancreatic β-cell function via estrogen receptors (ERs). However, the risk of hormone dependent cancer precludes the use of general estrogen therapy as a chronic treatment for diabetes. To target E2 to β-cells without the undesirable effects of general...

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Detalles Bibliográficos
Autores principales:	Tiano, Joseph P., Tate, Chandra R., Yang, Bin S., DiMarchi, Richard, Mauvais-Jarvis, Franck
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429560/ https://www.ncbi.nlm.nih.gov/pubmed/25970118 http://dx.doi.org/10.1038/srep10211

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