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Vascular endothelial growth factor blockade alters magnetic resonance imaging biomarkers of vascular function and decreases barrier permeability in a rat model of lung cancer brain metastasis

BACKGROUND: Blockade of vascular endothelial growth factor (VEGF) to promote vascular normalization and inhibit angiogenesis has been proposed for the treatment of brain metastases; however, vascular normalization has not been well-characterized in this disease. We investigated the effect of treatme...

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Detalles Bibliográficos
Autores principales:	Pishko, Gregory L, Muldoon, Leslie L, Pagel, Michael A, Schwartz, Daniel L, Neuwelt, Edward A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429592/ https://www.ncbi.nlm.nih.gov/pubmed/25879723 http://dx.doi.org/10.1186/2045-8118-12-5

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