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Mechanisms of Autoantibody Production in Systemic Lupus Erythematosus

Autoantibodies against a panoply of self-antigens are seen in systemic lupus erythematosus, but only a few (anti-Sm/RNP, anti-Ro/La, anti-dsDNA) are common. The common lupus autoantigens are nucleic acid complexes and levels of autoantibodies can be extraordinarily high. We explore why that is the c...

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Detalles Bibliográficos
Autores principales:	Han, Shuhong, Zhuang, Haoyang, Shumyak, Stepan, Yang, Lijun, Reeves, Westley H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429614/ https://www.ncbi.nlm.nih.gov/pubmed/26029213 http://dx.doi.org/10.3389/fimmu.2015.00228

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