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Local estrogen metabolism in epithelial ovarian cancer suggests novel targets for therapy

Epithelial ovarian cancer (EOC) accounts for about 90% of malignant ovarian tumors, and estrogen is often implicated in disease progression. We therefore compared the potential for gating of estrogen action via pre-receptor metabolism in normal human ovarian surface epithelium (OSE), EOC and selecte...

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Detalles Bibliográficos
Autores principales:	Ren, Xia, Wu, Xuan, Hillier, Stephen G., Fegan, K. Scott, Critchley, Hilary O.D., Mason, J. Ian, Sarvi, Sana, Harlow, Christopher R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Pergamon 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429663/ https://www.ncbi.nlm.nih.gov/pubmed/25817828 http://dx.doi.org/10.1016/j.jsbmb.2015.03.010

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