New recurrent BRCA1/2 mutations in Polish patients with familial breast/ovarian cancer detected by next generation sequencing

BACKGROUND: Targeted PCR-based genetic testing for BRCA1 and BRCA2 can be performed at a lower cost than full gene testing; however, it may overlook mutations responsible for familial breast and/or ovarian cancers. In the present study, we report the utility of next generation sequencing (NGS) to id...

Descripción completa

Detalles Bibliográficos
Autores principales: Kluska, Anna, Balabas, Aneta, Paziewska, Agnieszka, Kulecka, Maria, Nowakowska, Dorota, Mikula, Michal, Ostrowski, Jerzy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429836/
https://www.ncbi.nlm.nih.gov/pubmed/25948282
http://dx.doi.org/10.1186/s12920-015-0092-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429836/
https://www.ncbi.nlm.nih.gov/pubmed/25948282
http://dx.doi.org/10.1186/s12920-015-0092-2

Ejemplares similares