Hepatic Insulin Signaling is Dispensable for Suppression of Glucose Output by Insulin in Vivo

Insulin signaling and nutrient levels coordinate the metabolic response to feeding in the liver. Insulin signals in hepatocytes to activate Akt, which inhibits Foxo1 suppressing hepatic glucose production (HGP) and allowing the transition to the postprandial state. Here we provide genetic evidence t...

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Detalles Bibliográficos
Autores principales: Titchenell, Paul M., Chu, Qingwei, Monks, Bobby R., Birnbaum, Morris J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429930/
https://www.ncbi.nlm.nih.gov/pubmed/25963408
http://dx.doi.org/10.1038/ncomms8078

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429930/
https://www.ncbi.nlm.nih.gov/pubmed/25963408
http://dx.doi.org/10.1038/ncomms8078

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