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The Day-Hospital of the University Hospital, Bobo Dioulasso: An Example of Optimized HIV Management in Southern Burkina Faso

OBJECTIVES: To evaluate the epidemiological evolution of patients with HIV (PtHIV), between 2002 and 2012, in a day-hospital that became an HIV reference centre for south-west Burkina Faso. MATERIALS AND METHODS: This was a retrospective study of PtHIV followed in the Bobo Dioulasso university hospi...

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Autores principales: Chas, Julie, Hema, Arsène, Slama, Laurence, Kabore, Nongondo Firmin, Lescure, François-Xavier, Fontaine, Camille, Pialoux, Gilles, Sawadogo, Adrien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430172/
https://www.ncbi.nlm.nih.gov/pubmed/25970181
http://dx.doi.org/10.1371/journal.pone.0125588
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author Chas, Julie
Hema, Arsène
Slama, Laurence
Kabore, Nongondo Firmin
Lescure, François-Xavier
Fontaine, Camille
Pialoux, Gilles
Sawadogo, Adrien
author_facet Chas, Julie
Hema, Arsène
Slama, Laurence
Kabore, Nongondo Firmin
Lescure, François-Xavier
Fontaine, Camille
Pialoux, Gilles
Sawadogo, Adrien
author_sort Chas, Julie
collection PubMed
description OBJECTIVES: To evaluate the epidemiological evolution of patients with HIV (PtHIV), between 2002 and 2012, in a day-hospital that became an HIV reference centre for south-west Burkina Faso. MATERIALS AND METHODS: This was a retrospective study of PtHIV followed in the Bobo Dioulasso university hospital since 2002. The study was based on clinical data recorded using ESOPE software and analysed using Excel and SAS. RESULTS: A total of 7320 patients have been treated at the centre since 2002; the active file of patients increased from 147 in 2002 to 3684 patients in 2012. Mean age was stable at 38.4 years and the majority were female (71%). The delay to initiation of antiretroviral (ARV) treatment after HIV diagnosis decreased from 12.9 months in 2002 to 7.2 months in 2012. The percentage of PtHIV lost to follow-up, untreated for HIV and deaths all decreased after 2005. Voluntary anonymous screening and/or an evocative clinical picture were the main reasons for HIV diagnosis, usually at a late stage (41.1% at WHO stage 3). Virological success increased due to a decrease in time to initiation of ARV treatment and an increase in percentage of patients treated (90.5% in 2012, mainly with 1(st) line drugs). However, there was also a slight increase in the rate of therapeutic failures and the percentage of patients who progressed to 2(nd) or 3(rd) line-ARVs. CONCLUSION: Our day-hospital is a good example of the implementation of a specialist centre for the management of PtHIV in a resource-limited country (Burkina Faso).
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spelling pubmed-44301722015-05-21 The Day-Hospital of the University Hospital, Bobo Dioulasso: An Example of Optimized HIV Management in Southern Burkina Faso Chas, Julie Hema, Arsène Slama, Laurence Kabore, Nongondo Firmin Lescure, François-Xavier Fontaine, Camille Pialoux, Gilles Sawadogo, Adrien PLoS One Research Article OBJECTIVES: To evaluate the epidemiological evolution of patients with HIV (PtHIV), between 2002 and 2012, in a day-hospital that became an HIV reference centre for south-west Burkina Faso. MATERIALS AND METHODS: This was a retrospective study of PtHIV followed in the Bobo Dioulasso university hospital since 2002. The study was based on clinical data recorded using ESOPE software and analysed using Excel and SAS. RESULTS: A total of 7320 patients have been treated at the centre since 2002; the active file of patients increased from 147 in 2002 to 3684 patients in 2012. Mean age was stable at 38.4 years and the majority were female (71%). The delay to initiation of antiretroviral (ARV) treatment after HIV diagnosis decreased from 12.9 months in 2002 to 7.2 months in 2012. The percentage of PtHIV lost to follow-up, untreated for HIV and deaths all decreased after 2005. Voluntary anonymous screening and/or an evocative clinical picture were the main reasons for HIV diagnosis, usually at a late stage (41.1% at WHO stage 3). Virological success increased due to a decrease in time to initiation of ARV treatment and an increase in percentage of patients treated (90.5% in 2012, mainly with 1(st) line drugs). However, there was also a slight increase in the rate of therapeutic failures and the percentage of patients who progressed to 2(nd) or 3(rd) line-ARVs. CONCLUSION: Our day-hospital is a good example of the implementation of a specialist centre for the management of PtHIV in a resource-limited country (Burkina Faso). Public Library of Science 2015-05-13 /pmc/articles/PMC4430172/ /pubmed/25970181 http://dx.doi.org/10.1371/journal.pone.0125588 Text en © 2015 Chas et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Chas, Julie
Hema, Arsène
Slama, Laurence
Kabore, Nongondo Firmin
Lescure, François-Xavier
Fontaine, Camille
Pialoux, Gilles
Sawadogo, Adrien
The Day-Hospital of the University Hospital, Bobo Dioulasso: An Example of Optimized HIV Management in Southern Burkina Faso
title The Day-Hospital of the University Hospital, Bobo Dioulasso: An Example of Optimized HIV Management in Southern Burkina Faso
title_full The Day-Hospital of the University Hospital, Bobo Dioulasso: An Example of Optimized HIV Management in Southern Burkina Faso
title_fullStr The Day-Hospital of the University Hospital, Bobo Dioulasso: An Example of Optimized HIV Management in Southern Burkina Faso
title_full_unstemmed The Day-Hospital of the University Hospital, Bobo Dioulasso: An Example of Optimized HIV Management in Southern Burkina Faso
title_short The Day-Hospital of the University Hospital, Bobo Dioulasso: An Example of Optimized HIV Management in Southern Burkina Faso
title_sort day-hospital of the university hospital, bobo dioulasso: an example of optimized hiv management in southern burkina faso
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430172/
https://www.ncbi.nlm.nih.gov/pubmed/25970181
http://dx.doi.org/10.1371/journal.pone.0125588
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