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Differential Effects of Tra2ß Isoforms on HIV-1 RNA Processing and Expression

Balanced processing of HIV-1 RNA is critical to virus replication and is regulated by host factors. In this report, we demonstrate that overexpression of either Tra2α or Tra2β results in a marked reduction in HIV-1 Gag/ Env expression, an effect associated with changes in HIV-1 RNA accumulation, alt...

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Detalles Bibliográficos
Autores principales: Platt, Craig, Calimano, Maria, Nemet, Josip, Bubenik, Jodi, Cochrane, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430212/
https://www.ncbi.nlm.nih.gov/pubmed/25970345
http://dx.doi.org/10.1371/journal.pone.0125315

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